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. 1983 Oct;105(2):345–356. doi: 10.1093/genetics/105.2.345

Genetic Analysis of B2t, the Structural Gene for a Testis-Specific β-Tubulin Subunit in DROSOPHILA MELANOGASTER

Kenneth J Kemphues 1, Elizabeth C Raff 1, Thomas C Kaufman 1
PMCID: PMC1202161  PMID: 6414882

Abstract

Genetic analysis of the B2t locus has resulted in the recovery of four recessive mutations in the B2t structural gene and a deficiency that deletes the locus. Two of the mutations were recovered as suppressors of B2tD, a dominant male sterile mutation at the locus, and two were induced on wild-type chromosomes. All four mutant genes encode β2-tubulin subunits that are synthesized at normal rates but do not accumulate. All mutants are completely male sterile as homozygotes.

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Selected References

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