. 2025 Apr 11;15:1476402. doi: 10.3389/fonc.2025.1476402

Table 3.

The clinical response to different first-line therapy regimens in young unresectable gastric cancer patients.

Group	ORR (N=23)		p value ^b	DCR (N=104)		p value ^b
Group	Events (%)	95% CI ^a	p value ^b	Events (%)	95% CI ^a	p value ^b
Doublet chemotherapy	10 (15.9)	6.6%-25.2%	0.895	45 (71.4)	60.0%-82.9%	0.787
PD-1 inhibitor plus doublet chemotherapy	4 (12.5)	0.4%-24.6%	0.252	22 (68.8)	51.8%-85.7%	0.003
Triplet regimen	9 (23.1)	9.2%-36.9%	0.364	37 (94.9)	87.6%-102.1%	0.004

ORR, objective response rate; DCR, disease control rate; CI, confidence interval; PS, performance status; PD-1, programmed death 1.

^a 95% confidence interval with the Clopper-Pearson exact method, the true probability of ORR or DCR falls within the interval with 95% probability; ^b Chi-square test, or exact chi-square test if any expected cell size <5.