Table 7.
Comparison of baseline characteristics of patients grouped by eGFR.
| Variable | NRF group (n = 44) | DRF group (n = 82) | Z/χ2/t | p-value |
|---|---|---|---|---|
| Age (years) | 54.98 ± 10.456 | 61.93 ± 11.027 | 3.433 | 0.001 |
| Gender | 1.299 | 0.254 | ||
| Male (%) | 25 (56.82) | 55 (67.07) | ||
| Female (%) | 19 (43.18) | 27 (32.93) | ||
| BMI (kg/m2) | 26.157 ± 3.795 | 25.621 ± 3.627 | −0.778 | 0.438 |
| SBP (mmHg) | 135 (115, 144) | 143.5 (130.25, 155) | −3.077 | 0.002 |
| DBP (mmHg) | 81.480 ± 13.941 | 76.700 ± 11.331 | −2.081 | 0.040 |
| Hb (g/L) | 143.570 ± 21.118 | 112.490 ± 23.667 | −7.29 | <0.001 |
| PLT (109/L) | 241 (196, 276) | 223 (195, 252.25) | −1.269 | 0.204 |
| FPG (mmol/L) | 10.53 (7.83, 15.82) | 9.6 (7.04, 12.445) | −2.835 | 0.005 |
| UREA (mmol/L) | 5.49 (4.8125, 6.4025) | 13.305 (7.875, 23.9) | −7.152 | <0.001 |
| UA (μmol/L) | 318.368 ± 78.615 | 414.757 ± 89.782 | 5.992 | <0.001 |
| TP (g/L) | 70.777 ± 6.743 | 64.085 ± 8.031 | −4.706 | <0.001 |
| Scr (μmol/L) | 60.7 (51.9, 68.6) | 97.95 (79.4, 167.65) | −8.595 | <0.001 |
| eGFR (mL/min/1.73m2) | 103.7611 (96.893, 116.501) | 58.878 (33.767, 75.285) | −9.232 | <0.001 |
| IL6 (pg/mL) | 3.06 (1.5, 6.87) | 3.855 (2.545, 6.0725) | −3.085 | 0.002 |
| SII | 491.167 (341.667, 715.826) | 548.084 (427.025, 928.193) | −2.83 | 0.005 |
| CysC (10 mg/L) | 8.1 (7.0, 9.7) | 17.4 (12.05, 24.45) | −8.751 | <0.001 |
| 24-UTP (mg) | 138 (70, 212) | 1,002 (171.25, 3,920) | −7.039 | <0.001 |
| UACR (mg/g) | 80 (15, 150) | 550 (85, 800) | −4.756 | <0.001 |
| TGF-β1 (ng/mL) | 27.663 ± 10.138 | 37.249 ± 12.569 | 4.354 | <0.001 |
BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; WBC, white blood cell count; Hb, hemoglobin; PLT, platelet count; FPG, fasting plasma glucose; UA, uric acid; TP, total protein; Scr, serum creatinine; eGFR, estimated glomerular filtration rate; IL6, interleukin-6; SII, systolic index of inflammation; CysC, cystatin C; 24-UTP, 24-h urinary total protein; UACR, urine albumin creatinine ratio; TGF-β1, transforming growth factor beta 1.