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. 2025 Apr 11;12:1529648. doi: 10.3389/fmed.2025.1529648

Table 9.

Diagnostic performance of TGF-β1 and CysC in predicting renal function decline.

Index AUC p-value 95% CI Optimal cut-off value Sensitivity Specificity Youden index
TGF-β1 0.726 <0.001 0.637–0.815 35.43 ng/mL 0.634 0.864 0.498
CysC 0.974 <0.001 0.952–0.996 11.55 (10 mg/L) 0.890 0.955 0.845
TGF-β1 + CysC 0.974 <0.001 0.952–0.996 0.890 0.955 0.845

AUC, area under the curve; 95% CI, 95% confidence interval.