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. 2025 Apr 24;15:14376. doi: 10.1038/s41598-025-98699-1

Table 2.

Analysis of vitals and clinical data between groups.

Nicardipine (n = 40) Esmolol (n = 42) p
Mean ± sd/median (25–75) Mean ± sd/median (25–75)
Systolic BP (mmHg) 188 (182–199) 190 (185–200) 0.321m
Diastolic BP (mmHg) 109 (100–110) 105 (100–115) 0.765m
End systolic BP 157.0 ± 9.8 170.6 ± 6.7 < 0.001
End diastolic BP 83.7 ± 5.2 91.5 ± 5.3 < 0.001
BP control time (min) 19.0 ± 6.35 25.4 ± 8.7 < 0.001
Pulse 80 (76–90) 87 (80–97) 0.047 m
Tempereture ( C) 36.7 (36.7–36.9) 36.8 (36.7–36.9) 0.418m
Breathing (/min) 14 (13–16) 15 (14–18) 0.157m
Saturation 98 (96–99) 96 (96–99) 0.256m
NIHSS at admission 10.5 ± 5.9 12.8 ± 7.5 0.131
Symptom door duration (min) 63.1 ± 37.1 79.2 ± 42.0 0.070
Symptom needle Dur. (min) 160.5 ± 58.1 174.8 ± 48.2 0.228
Door needle duration (min) 97.4 ± 56.2 95.6 ± 41.04 0.866
Hospitalisation (day) 11 (7–21) 10 (7–16) 0.375m
mRS 3 (1–6) 3 (1–6) 0.691m
ICH (+) n(%) 14 (35%) 12 (28.6%) 0.698 χ2
Mortality (+) n(%) 13 (32.5%) 12 (28.6%) 0.699 χ2

Significant values are given in bold.

BP blood pressure, mRS modified Rankin scale, ICH intracerebral haemorrhage, Dur duration, Min minute.

†Independent T test.

mMann Whitney U.

χ2Chi-square test.