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. 2025 Apr 18;13(4):992. doi: 10.3390/biomedicines13040992

Table 1.

In vitro inhibitory activities of E1-E9 against UT-B (n = 3).

graphic file with name biomedicines-13-00992-i001.jpg
Compound R1 R2 R3 IC50 (μM) 1
Rat Mouse
25a H H graphic file with name biomedicines-13-00992-i002.jpg 0.14 0.48
E1 H H graphic file with name biomedicines-13-00992-i003.jpg 0.32 0.86
E2 H H graphic file with name biomedicines-13-00992-i004.jpg 0.40 2.41
E3 H graphic file with name biomedicines-13-00992-i005.jpg H 0.01 0.05
E4 graphic file with name biomedicines-13-00992-i006.jpg H H 6.46 >10
E5 H H graphic file with name biomedicines-13-00992-i007.jpg 0.06 0.23
E6 H OH graphic file with name biomedicines-13-00992-i008.jpg 0.05 0.18
E7 H H graphic file with name biomedicines-13-00992-i009.jpg 0.09 0.23
E8 H H graphic file with name biomedicines-13-00992-i010.jpg 0.77 2.55
E9 H H graphic file with name biomedicines-13-00992-i011.jpg 1.75 4.07

1 IC50 is tested with the erythrocyte lysis model. Data are means.