aa	Amino acid
ACLY	Adenosine triphosphate-citrate lyase
ADP	Adenosine Diphosphate
CVD	Cardiovascular disease
CHD	Congenital heart disease
Da	Dalton
DALYS	Disability-Adjusted Life Years
DHCR24	Dehydrocholesterol reductase24
EBP	Emopamil binding protein
EGF-A	Epidermal Growth Factor like-domain A
EMA	European Medicines Agency
FDA	Food and Drug Administration
GI	Gastrointestinal
h	Human
HMG-CoA	3-Hydroxy-3-Methyl Glutaryl Coenzyme A
IDL	Intermediate-density lipoprotein
IR	Immediate Release
LDL	Low-density lipoprotein
mAb	Monoclonal antibody
MHRA	Medicines and Healthcare products Regulatory Agency, UK
mRNA	Messenger Ribonucleic Acid
MW	Molecular weight
OSC	Oxidosqualene cyclase
PCSK9	Proprotein Convertase Subtilisin Kexin9
RISC	RNA-induced silencing complex
SNAC	Sodium N-(8-[2-hydroxybenzoyl] amino) caprylate
SQLE	Squalene epoxidase
SQS	Squalene synthase
tBu	Tertiary butyl
THPBs	Tetrahydroproto-berberines
VLDL	Very low-density lipoprotein