PSE	Perilla seed extract
UPLC-MS/MS	Ultra-performance liquid chromatography–tandem mass spectrometry
TCMSP	Traditional Chinese medicine systems pharmacology
PPI	Protein–protein interaction
H&E	Hematoxylin and eosin
PAS	Periodic acid–Schiff stain
GO	Gene Ontology
KEGG	Kyoto Encyclopedia of Genes and Genomes
BP	Biological process
CC	Cellular component
MF	Molecular function
LPS	Lipopolysaccharide
OB	Oral bioavailability
DL	Drug-likeness
DEGs	Differentially expressed genes