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. 2025 Apr 13;26(8):3675. doi: 10.3390/ijms26083675
SCD Sickle cell disease
HbS Sickle cell hemoglobin
sRBCs Sickle cell red blood cells
Hb Hemoglobin
RBCs Red blood cells
HBB β-globin
glutamic acid Glu
valine Val
adult hemoglobin HbA
ROS Free oxygen radicals
HbF Fetal hemoglobin
B-CAM-1/Lu Basal cell adhesion molecule-1/Lutheran
IAP Integrin-associated protein
ICAM-4 Intercellular adhesion molecule-4
VOC Vaso-occlusive crisis
VCAM-1 Vascular cell adhesion molecules-1
RNS Reactive nitrogen species
NADPH Nicotinamide-adenine dinucleotide phosphate
XO Xanthine oxidase
ADMA Asymmetric dimethylarginine
NOS Nitric oxide synthase
MetHb Methemoglobin
BH4 Tetrahydrobiopterin
Hp Haptoglobin
TF Transferrin
TFR1 Transferrin receptor 1
SLC11A2 Member 2 of the solute transporter family 11
LIPs Labile iron complexes
FTH1 Ferritin heavy chain 1
FTL Ferritin light chain
SLC40A1 Member 1 of the solute transporter family 40
NCOA4 Nuclear receptor 4
SLC25A37/mitoferrin-1 Solute transporter family 25 member 37
SLC25A28/mitoferrin-2 Solute transporter family 25 member 28
VDAC Voltage-dependent anion channels
NTBI Non-transferrin-bound iron
PUFAs Polyunsaturated fatty acids
PUFAs-OOH Lipid peroxides
HNE 4-hydroxynonenal
MDA Malondialdehyde
LPCAT3 Lysophosphatidylcholine acyltransferase 3
LOX Lipoxygenases
LOOH Lipid peroxides
SLC7A11 Solute Carrier Family 7 Member 11
SLC3A2 Solute Carrier Family 3 Member 2
MBOAT1 PL lysophospholipid acyltransferase 1
Nrf2 Nuclear factor erythroid 2-related factor 2
FTH1 Ferritin heavy chain 1
NQO1 Quinone oxidoreductase 1
HO-1 Heme oxygenase-1
TSS Transulfuration pathway
DMF Dimethyl fumarate
CBS De novo cysteine synthesis