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. 2025 Apr 13;26(8):3672. doi: 10.3390/ijms26083672
25(OH)D 25-hydroxyvitamin D
27-OHC 27-hydroxycholesterol
5LO 5-lipoxygenase
AA Anthranilic acid
AD Alzheimer’s disease
ADMA Asymmetric dimethylarginine
ALA Alpha-lipoic acid
ApoE Apolipoprotein E
APP Amyloid precursor protein
Amyloid β
BBB Blood–brain barrier
BHMT Betaine-homocysteine methyltransferase
CBF Cerebral blood flow
cECs Cerebral endothelial cells
CH2THF 5,10-Methylenetetrahydrofolate
CH3THF 5-methyltetrahydrofolate
CNS Central nervous system
COMT Catechol-O-methyltransferase
CSF Cerebrospinal fluid
DDAH Dimethylarginine dimethylaminohydodrolase
DMA Dimethylamine
DMG Dimethylglycine
DM-PP2Ac De-methylated PP2A catalytic subunit
DR4/5 Death receptor 4 and 5
EAE Autoimmune encephalomyelitis
EDSS Expanded Disability Status Score
ET Endothelin
FAD Flavin adenine dinucleotide
HAA 3-hydroxyanthranilic acid
HCs Healthy controls
HCTL Homocysteine thiolactone
Hcy Homocysteine
HHcy Hyperhomocysteinemia
HK 3-hydroxykynurenine
iNOS inducible Nitric Oxide Synthase
KA Kynurenic acid
KAT Kynurenine aminotransferase
Kyn kynurenine
KYNU Kynureninase
MBP Myelin basic protein
MCI Mild Cognitive Impairment
MeSe Methionine synthase
MMA Methylmalonic acid
MOG Myelin oligodendrocyte glycoprotein
M-PP2Ac Methylated PP2A catalytic subunit
MS Multiple sclerosis
MSSS Multiple Sclerosis Severity Score
MTHFR Methylenetetrahydrofolate reductase
NMO Neuromyelitis optica
NO Nitric oxide
NOS Nitric oxide synthase
ONDs Other neurologic diseases
PD Parkinson’s disease
PLP Pyridoxal 5-phosphate
PP2A Protein phosphatase 2A
PRMT-1 Protein arginine methyltransferases-1
PRMT-4 Protein arginine methyltransferase-4
PS1 Presenilin 1
pS262-tau Ser262 hyperphosphorylated tau
PTMs Post-translational modifications
ROS Reactive oxygen species
RR Relapsing–remitting
SAH S-adenosyl homocysteine
SAM S-adenosyl methionine
SDMA Symmetric dimethylarginine
SP Secondary progressive
TCA Tricarboxylic acid
THF Tetrahydrofolate
tHcy Total homocysteine
VCID Cognitive impairment and dementia
XA Xanthurenic acid