TABLE 1.
Sequence analysis of rifampin-resistant M. tuberculosis isolates from four East Asian countries and regions
| Amino acid substitution | No. (%) of isolates | Origin of isolates (no. of isolates) |
|---|---|---|
| Gln513Leu | 1 (1.5) | China (1) |
| Gln513Lys | 3 (4.5) | China (3) |
| 514-Phe ins.a | 1 (1.5) | Taiwan (1) |
| Asp516Ala | 6 (9.1) | China (1), Korea (3), Taiwan (2) |
| Asp516Tyr | 5 (7.6) | China (3), Korea (1), Taiwan (1) |
| His526Arg | 1 (1.5) | Taiwan (1) |
| His526Asn | 1 (1.5) | Korea (1) |
| His526Leu | 2 (3.0) | Korea (2) |
| His526Tyr | 3 (4.5) | China (1), Japan (1), Taiwan (1) |
| Ser531Gln | 1 (1.5) | Taiwan (1) |
| Ser531Leu | 33 (50.0) | China (14), Japan (2), Korea (10), Taiwan (7) |
| Leu533Pro | 2 (3.0) | Taiwan (2) |
| None | 7 (10.6) | China (2), Korea (1), Taiwan (4) |
a
Phenylalanine insertion.