Figure 3.

Genus-level microbiota composition has significantly different relative abundance among the four groups. (a) The top 20 genera have significant differences among the four groups. The Kruskal–Wallis test with FDR was used to compare differences among groups, and Welch’s (uncorrected) test was used as a post hoc test. * p < 0.05, ** p < 0.01, *** p < 0.001. (b) Relative abundance shift patterns for the top 10 genera across the four groups.Each point in the figure shows the relative abundance of the bacterial phylum in the sample. The blue trend line is the fitted curve of the average relative abundance, and the gray shaded area shows the interval of the standard deviation.