Figure 3.

Analysis of carnitine/acylcarnitine metabolites in MCF-7 samples. (A) Heatmap of 16 carnitine/acylcarnitine metabolites across all four treatment groups. Data are auto-scaled (mean-centered and divided by standard deviation) for each metabolite. (B) PCA plot of all four treatment groups using the 16 carnitine/acylcarnitine metabolites. Green = 0 μM, blue = 1 μM, red = 10 μM, yellow = 100 μM. (C) Biplot showing the loadings of each carnitine/acylcarnitine metabolite on top of the PCA from Figure 3B. Individual metabolites are indicated in purple. All multivariate plots were scaled to unit variance. Axis labels p(corr) [1],t(corr) [1] and p(corr) [2],t(corr) [2] refer to the correlation-scaled loadings (p) and scores (t) of the first and second principal components, respectively.