Table 3.
Changes in carnitine metabolites in MDA-MB-231 cells treated with varying doses of resveratrol.
| Fold Change | p-Value | VIP | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Metabolite Name | Ontology Level | 25 µM/ 0 µM |
50 µM/ 0 µM |
100 µM/ 0 µM |
0 µM vs. 25 µM |
0 µM vs. 50 µM |
0 µM vs. 100 µM |
0 µM vs. 25 µM |
0 µM vs. 50 µM | 0 µM vs. 100 µM |
| Octadecanoylcarnitine | OL1 | 1.91 | 6.89 | 7.61 | 0.13 | 4.6 × 10−4 | 2.5 × 10−5 | 0.98 | 1.43 | 1.42 |
| Oleoylcarnitine | OL1 | 0.61 | 2.43 | 4.68 | 0.43 | 0.057 | 7.9 × 10−4 | 0.87 | 1.18 | 1.37 |
| Hexadecanoylcarnitine | OL1 | 2.36 | 5.93 | 8.40 | 7.4 × 10−3 | 1.2 × 10−4 | 4.6 × 10−7 | 1.37 | 1.47 | 1.45 |
| Myristoylcarnitine | OL1 | 3.27 | 7.65 | 12.96 | 1.7 × 10−5 | 4.5 × 10−6 | 6.7 × 10−8 | 1.52 | 1.49 | 1.45 |
| Butenylcarnitine | OL2a | 1.00 | 0.91 | 1.27 | 0.96 | 0.45 | 5.9 × 10−3 | 0.64 | 0.89 | 1.27 |
| Valerylcarnitine | OL1 | 0.69 | 0.49 | 0.33 | 3.5 × 10−4 | 3.9 × 10−6 | 7.4 × 10−7 | 1.48 | 1.50 | 1.45 |
| Tiglylcarnitine | OL1 | 0.91 | 1.37 | 1.71 | 0.15 | 7.2 × 10−5 | 1.6 × 10−4 | 1.06 | 1.47 | 1.41 |
| Isobutyrylcarnitine | OL1 | 1.21 | 2.20 | 2.45 | 1.2 × 10−3 | 2.2 × 10−7 | 2.8 × 10−7 | 1.45 | 1.51 | 1.45 |
| Propionylcarnitine | OL1 | 0.67 | 0.52 | 0.35 | 1.0 × 10−5 | 8.1 × 10−8 | 2.8 × 10−9 | 1.52 | 1.51 | 1.45 |
| O-Acetylcarnitine | OL1 | 0.72 | 0.72 | 0.66 | 0.015 | 0.011 | 0.017 | 1.28 | 1.30 | 1.19 |
| Carnitine | OL1 | 0.87 | 0.71 | 0.52 | 0.27 | 8.6 × 10−3 | 3.1 × 10−4 | 0.96 | 1.32 | 1.39 |
| Deoxycarnitine | OL1 | 0.90 | 0.91 | 0.75 | 0.11 | 0.66 | 2.1 × 10−2 | 1.06 | 0.58 | 1.16 |