Skip to main content
. 2025 Apr 11;13(4):301. doi: 10.3390/toxics13040301
3D Three-dimensional
6PPD N-(1,3-dimethylbutyl)-N′-phenyl-1,4-phenylenediamine
6PPDQ 6PPD quinone
ABC ATP binding cassette
ABS Stone mastic asphalt
ABT Asphalt concrete
AChE Acetyl-cholinesterase
ALP Alkaline phosphatase
ALT Alanine aminotransferase
ARG Antibiotic-resistant gene
AST Aspartate aminotransferase
ATP Adenosine triphosphate
BALF Bronchoalveolar lavage fluid
BPA Bisphenol A
BPAF Bisphenol AF
BPF Bisphenol F
BPS Bisphenol S
BT Benzothiazole
Car Carotenoids
CAT Catalase
CAV-1 Caveolin-1
CD55 Lipid raft marker
Chla Chlorophyll a
DCFH-DA 2′7′-dichlorodihydrofluorescein diacetate
DEGs Differentially expressed genes
DFO Deferoxamine
DFX Deferoxamine mesylate
DNA Deoxyribonucleic acid
DPG 1,3-diphenylguanidine
DRM Detergent-resistant membrane
DTBBA Dithiobisbenzanilide
EC50 50% effect concentration
ECE Economic Commission for Europe
EDTA Ethylene diammine tetra acetic acid
EPFRs Environmentally persistent free radicals
EU European Union
FETAX Frog embryo teratogenesis assay—Xenopus
FLOT-1 Flottilin-1
FTIR Fourier-transform infrared spectroscopy
GGT γ -glutamyl transpeptidase
GO Gene ontology
GPx Glutathione peroxidase
GSH Glutathione
GST Glutathione S-transferase
hAO Human airway organoid
HO-1 Heme oxygenase-1
Hsp70 Heat shock protein 70
IL-8 Interleukine-8
LC50 Lethal concentration for 50% of the test subjects
LDH Lactate dehydrogenase
LM Low-metallic
LMS Lysosomal membrane stability
LOEC Lowest observed effect concentration
MBT 2-mercaptobenzothiazole
MDA Malondialdehyde
MDDC Monocyte-derived dendritic cell
MDM Monocyte-derived macrophage
MEF Membrane-enriched fraction
MIP-2 Macrophage inflammatory protein-2
MMI Methimazole
mRNA Messenger ribonucleic acid
MTT 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
NAG β-N-acetylglucosaminidase
NAO Non-asbestos organic
NO Nitrogen oxide
NOEC Non-observable effect concentration
OECD Organisation for Economic Co-operation and Development
PAHs Polycyclic aromatic hydrocarbons
PEF Peak expiratory flow
PET Polyethylene terephthalate
PM Particulate matter
PMN Polymorphonuclear neutrophilic leukocyte
PVC Polyvinyl chloride
ROS Reactive oxygen species
SOD Superoxide dismutase
SM Semi-metallic
TBARSs Thiobarbituric acid reactive substances
TC50 Teratogenic concentration for 50% of a test species
TIE Toxicity identification evaluation
TNF-α Tumour necrosis factor alpha
TOF-MS Time-of-flight mass spectrometry
TPs Tyre particles
TPO Thyroid peroxidase
TRWPs Tyre and road wear particles
TWPs Tyre wear particles
USA United States of America
UV Ultraviolet
VACES Versatile ambient concentration enrichment system
VTI Swedish National Road and Transport Research Institute
WHO World Health Organization