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. 2025 Apr 26;25:510. doi: 10.1186/s12884-025-07189-9

Table 3.

Scenario results on the annual health and economic burden of postpartum hemorrhage in Senegal

PPH ≥ 500 ml PPH ≥ 1000 ml Additional uterotonic treatment Blood transfusions Deaths due to PPH Total economic burden of PPH Total OOP costs public Total OOP costs private Long term productivity loss
0. Baseline estimate 86,542 21,152 35,250 14,408 447 $19,499,322 $1,774,990 $833,766 $16,890,566
1. No substandard uterotonics 81,540 19,769 29,331 9,643 418 $18,221,486 $1,615,355 $787,498 $15,818,633
Difference -5,002 -1,383 -5,918 -4,765 -28 -$1,277,836 -$159,634 -$46,268 -$1,071,933
Difference % -6% -7% -17% -33% -6% -7% -9% -6% -6%
2. Quality misoprostol + oxytocin for facility births 75,117 19,005 25,647 8,470 402 $17,273,438 $1,408,674 $678,574 $15,186,190
Difference -11,425 -2,146 -9,603 -5,938 -45 -$2,225,883 -$366,315 -$155,192 -$1,704,376
Difference % -13% -10% -27% -41% -10% -11% -21% -19% -10%
3. Quality heat-stable carbetocin for facility births 76,250 19,334 26,277 8,669 408 $17,619,801 $1,463,591 $711,814 $15,444,396
Difference -10,292 -1,818 -8,972 -5,738 -38 -$1,879,521 -$311,398 -$121,952 -$1,446,170
Difference % -12% -9% -25% -40% -9% -10% -18% -15% -9%
4. Misoprostol at reported level of quality for home births 74,344 20,132 35,009 14,231 426 $18,701,065 $1,766,432 $832,082 $16,102,551
Difference -12,198 -1,020 -241 -177 -21 -$798,257 -$8,557 -$1,685 -$788,015
Difference % -14% -5% -1% -1% -5% -4% 0% 0% -5%
5. Quality misoprostol for home births 72,005 19,526 34,888 14,139 412 $18,168,530 $1,762,548 $833,887 $15,572,094
Difference -14,537 -1,626 -362 -269 -35 -$1,330,792 -$12,441 $121 -$1,318,471
Difference % -17% -8% -1% -2% -8% -7% -1% 0% -8%
6. All deliveries happen in facilities 70,632 19,117 44,603 18,114 405 $18,475,308 $2,229,428 $951,006 $15,294,874
Difference -15,910 -2,035 9,353 3,706 -42 -$1,024,014 $454,438 $117,239 -$1,595,692
Difference % -18% -10% 27% 26% -9% -5% 26% 14% -9%
7. All deliveries happen in facilities with quality-assured uterotonics 64,110 17,370 36,938 11,933 367 -$16,799,964 $2,023,821 $896,540 $13,879,602
Difference -22,431 -3,782 1,689 -2,475 -80 -$2,699,358 $248,832 $62,774 -$3,010,964
Difference % -26% -18% 5% -17% -18% -14% 14% 8% -18%

OOP: out-of-pocket; PPH: postpartum hemorrhage

Scenario descriptions: (1) No substandard uterotonics: The uterotonics provided at healthcare facilities are quality assured. (2) Quality misoprostol + oxytocin for facility births: All women in facilities receive both misoprostol and oxytocin, and they are quality assured. (3) Quality heat-stable carbetocin for facility births: All women in facilities receive heat-stable carbetocin and it is quality assured. (4) Misoprostol at reported level of quality for home births: Home birthing women utilize misoprostol at reported level of quality. (5) Quality misoprostol for home births: Home birthing women utilize quality-assured misoprostol. (6) All deliveries happen in facilities: All women are modeled to utilize facility care. The use and quality of uterotonics in facilities remain as baseline. (7) All deliveries happen in facilities with quality-assured uterotonics: All women are modeled to utilize facility care. The use of uterotonics in facilities remains at baseline. The uterotonics provided are quality-assured.