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. 2025 Jan-Feb;15(2):1030–1046. doi: 10.22038/AJP.2024.24940

Table 2.

Percentage of lesion size reduction and parasite burden among the different groups of CLmouse model exposed to different concentrations of extracts (leaves, roots and seeds of Arctium lappa).

Type of extract Concentrations (µg/ml) Reduction in Lesion size (%) Spleen parasite burden (LU) Liver parasite burden (LU)
50 25% 260±3.5 252±4
Seeds 100 26% 245±2.78 245±2.9
200 29% 230±4.2 220±3.48
Leaves 50
100
200
30%
31%
35%
195±5
190±1.72
185±2.28
182±2.42
180±3.42
170±5.2
Roots 50
100
200
27%
28%
31%
235±2.25
220±6.78
195±3
210±3
190±8.92
180±2.78

CL, Cutaneous Leishmaniasis. Note: The highest reduction in lesion size (%) and parasite burden in CL mouse model was respectively related to groups treated with Glucantime, extracts of leaves, roots and finally seeds of Arctium lappa. (in Table each point represents the mean±SD of at least three experiments).