Table 2.
Comparison of PDFF, RBF values in renal cortex and medulla, and perirenal fat thickness in four groups (x̅ ± s)
| Group | PDFF (%) | RBF (mL/100 g/min) | Perirenal fat thickness (mm) | ||
|---|---|---|---|---|---|
| Cortex | Medulla | Cortex | Medulla | ||
| HC | 0.88 ± 0.09 | 0.86 ± 0.10 | 182.97 ± 47.29 | 42.62 ± 4.11 | 6.39 ± 3.18 |
| T2DM | 1.22 ± 0.09a | 1.18 ± 0.09a | 158.61 ± 29.03a | 35.71 ± 1.45a | 10.33 ± 5.79a |
| DKDI-II | 1.53 ± 0.13a,b | 1.56 ± 0.14a,b | 137.04 ± 14.57a,b | 30.59 ± 2.97a,b | 14.49 ± 6.31a,b |
| DKDIII-IV | 1.74 ± 0.08a,b,c | 1.75 ± 0.10a,b,c | 116.23 ± 13.55a,b,c | 27.79 ± 1.67a,b,c | 23.65 ± 6.27a,b,c |
| F | 300.233 | 288.135 | 17.287 | 124.587 | 31.848 |
| p* | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
Notes: Data are presented as the number, mean ± standard deviation. Means with different letters indicate significant differences between the groups
* LSD multiple pairwise comparison tests were used for statistical significance ANOVA
RBF renal blood flow, PDFF proton-density fat fraction, HC Healthy control, T2DM type 2 diabetes mellitus, DKD diabetic kidney disease
a Significant difference from HC (p < 0.05)
b Significant difference from T2DM (p < 0.05)
C Significant difference from DKDI-II (p < 0.05)