Table 3.
Disproportionality analysis
| Oral | Subcutaneous | ||||
|---|---|---|---|---|---|
| PTs | N(%) | ROR (95%CI) | PTs | N(%) | ROR (95%CI) |
| Vision blurred | 69(34.33) | 4.15(3.27–5.25) | Vision blurred | 433(26.84) | 2.58(2.35–2.84) |
| Visual impairment | 38(18.91) | 2.45(1.78–3.37) | Visual impairment | 392(24.30) | 2.51(2.27–2.78) |
| Blindness | 10(4.98) | 2.03(1.09–3.78) | Cataract | 98(6.08) | 1.37(1.12–1.67) |
| Diabetic retinopathy | 8(3.98) | 18.99(9.49–38.02) | Diabetic retinopathy | 76(4.71) | 18.31(14.58–23.00) |
| Eye haemorrhage | 6(2.99) | 3.55(1.60–7.92) | Blindness | 69(4.28) | 1.39(1.10–1.76) |
| Dry eye | 6(2.99) | 1.12(0.50–2.50) | Retinopathy | 56(3.47) | 11.93(9.16–15.54) |
| Blindness unilateral | 5(2.49) | 2.88(1.20–6.93) | Eye pain | 37(2.29) | 0.57(0.41–0.79) |
| Eye pain | 5(2.49) | 0.78(0.32–1.86) | Diplopia | 36(2.23) | 1.12(0.81–1.55) |
| Cataract | 5(2.49) | 0.70(0.29–1.69) | Dry eye | 36(2.23) | 0.67(0.48–0.93) |
| Diplopia | 4(2.00) | 1.25(0.47–3.33) | Eye haemorrhage | 31(1.92) | 1.83(1.28–2.60) |
| Vitreous haemorrhage | 4(2.00) | 11.70(4.39–31.21) | Blindness unilateral | 30(1.86) | 1.72(1.20–2.46) |
| Eye swelling | 4(2.00) | 0.88(0.33–2.35) | Ischemic neuropathy | 30(1.86) | 9.15(6.38–13.12) |
| Visual acuity reduced | 3(1.49) | 0.67(0.22–2.09) | Eye disorder | 27(1.67) | 0.67(0.46–0.98) |
| Ocular hyperaemia | 3(1.49) | 0.55(0.18–1.70) | Vitreous floaters | 23(1.43) | 1.95(1.29–2.93) |
| Vitreous floaters | 3(1.49) | 2.56(0.82–7.93) | Retinal detachment | 20(1.24) | 1.79(1.15–2.77) |
| Macular degeneration | 3(1.49) | 2.15(0.69–6.68) | Vitreous haemorrhage | 19(1.18) | 5.55(3.53–8.71) |
| Blindness transient | 2(1.00) | 2.20(0.55–8.79) | Eye pruritus | 18(1.12) | 0.49(0.31–0.77) |
| Visual field defect | 2(1.00) | 1.96(0.49–7.85) | Ocular hyperaemia | 17(1.05) | 0.31(0.19–0.50) |
| Glaucoma | 2(1.00) | 0.84(0.21–3.35) | Photophobia | 17(1.05) | 0.75(0.47–1.21) |
| Retinal haemorrhage | 2(1.00) | 2.26(0.57–9.06) | Eye swelling | 17(1.05) | 0.37(0.23–0.60) |
| Photophobia | 2(1.00) | 0.89(0.22–3.55) | Lacrimation increased | 17(1.05) | 0.48(0.30–0.77) |
| Vitreous detachment | 2(1.00) | 7.63(1.91–30.53) | Glaucoma | 16(1.00) | 0.67(0.41–1.09) |
| Retinal tear | 2(1.00) | 6.77(1.69–27.09) | Eye irritation | 15(0.93) | 0.24(0.15–0.40) |
| Eye disorder | 2(1.00) | 0.50(0.12–2.00) | Macular degeneration | 13(0.81) | 0.93(0.54–1.60) |
| Ocular discomfort | 2(1.00) | 1.70(0.43–6.81) | Retinal tear | 13(0.81) | 4.39(2.54–7.57) |
| Lacrimation increased | 2(1.00) | 0.57(0.14–2.27) | Blindness transient | 12(0.74) | 1.31(0.74–2.31) |
| Miosis | 2(1.00) | 2.11(0.53–8.43) | Retinal haemorrhage | 12(0.74) | 1.35(0.77–2.38) |
| Photopsia | 1(0.50) | 1.27(0.18–8.98) | Ocular discomfort | 12(0.74) | 1.01(0.58–1.79) |
| Accommodation disorder | 1(0.50) | 10.63(1.50–75.60) | Macular oedema | 11(0.68) | 1.60(0.89–2.90) |
| Myopia | 1(0.50) | 3.35(0.47–23.81) | Vitreous detachment | 10(0.62) | 3.80(2.04–7.07) |