Table 2.
Parameters at maximum load for obese patients, DMTII patients and healthy subjects
| Obese (mean ± SD) | DMT II (mean ± SD) | Significance (p) Obese – DMT II |
Healthy (mean ± SD) | Significance (p) Healthy – patient groups |
|
|---|---|---|---|---|---|
| RRsys (mmHg) | 204 ± 24 | 196 ± 30 | n.s. | 204 ± 27 | n.s. |
| RRdia (mmHg) | 95 ± 13 | 90 ± 15 | n.s. | 69 ± 6 | p < 0.01 |
| MAP (mmHg) | 140 ± 14 | 133 ± 16 | n.s. | 128 ± 12.5 | p < 0.01 |
| Power output (W) | 108 ± 33 | 89 ± 24 | p < 0.01 | 268 ± 55 | p < 0.01 |
| Oxygen consumption (ml/min) | 1800 ± 421 | 1543 ± 348 | p < 0.01 | 3277 ± 850 | p < 0.01 |
| Respiratory exchange ratio | 0.95 ± 0.12 | 0.96 ± 0.12 | n.s. | 1.11 ± 0.09 | p < 0.01 |
| Lactate (mmol/l) | 3.52 ± 1.74 | 4.07 ± 1.47 | n.s. | 9.58 ± 1.82 | p < 0.01 |
| HR (1/min) | 129 ± 18 | 120 ± 15 | p < 0.02 | 188 ± 9 | p < 0.01 |
| SV (ml) | 143 ± 27 | 136 ± 29 | n.s. | 96 ± 23 | p < 0.01 |
| CO (l/min) | 18.13 ± 3.45 | 16.26 ± 3.50 | p < 0.04 | 18.19 ± 4.61 | n.s. |
| avDO2 (ml/dl) | 10.45 ± 2.74 | 9.65 ± 1.89 | n.s. | 18.22 ± 3.25 | p < 0.01 |
| SW (Nm) | 2.73 ± 0.54 | 2.40 ± 0.65 | p < 0.03 | 1.68 ± 0.49 | p < 0.01 |
| VET (ms) | 217 ± 45 | 230 ± 46 | n.s. | 189 ± 25 | p < 0.01 |
| SPO (W) | 13.18 ± 3.01 | 11.00 ± 4.36 | p < 0.03 | 8.90 ± 2.57 | p < 0.04 |
| CPO (W) | 5.67 ± 1.17 | 4.81 ± 1.37 | p < 0.01 | 5.27 ± 1.66 | n.s. |
| TPR (mmHg/l/min) | 8.1 ± 1.9 | 8.5 ± 2.0 | n.s. | 7.5 ± 1.9 | n.s. |
Data presented as mean (standard deviation); RRsys: systolic blood pressure; RRdia: diastolic blood pressure; MAP: mean arterial pressure; HR: heart rate; SV: stroke volume; CO: cardiac output; avDO2: arteriovenous oxygen difference; SW: Stroke Work; VET: left ventricular ejection time; SPO: Stroke power output; CPO: cardiac power output; TPR: Total peripheral resistance