Table 3.

EC₉₅ of Propofol for Smooth Intubation in Different Dexmedetomidine Groups Calculated Using Biased Coin Design Method

Groups	EC95 (95% CI) of Propofol (μg/mL)	Propofol Dose (mg/kg)
A	14.9 (4.5, 15.0)*	3.8±0.9*
B	14.6 (10.8, 14.8)#	3.6±1.1#
C	12.7 (11.5, 12.8)	2.8±1.0

Notes: *P<0.001 vs Dexmedetomidine 1μg/kg; ^#P<0.001 vs Dexmedetomidine 1μg/kg, P<0.017 is considered significant according to the Bonferroni correction factor; Group A, dexmedetomidine 0.6μg/kg; Group B, dexmedetomidine 0.8μg/kg; Group C, dexmedetomidine 1.0μg/kg.

Abbreviations: EC₉₅, effective concentration in 95% of patients; CI, confidence interval.