Fig. 7. NM102 is not toxic to the host.
A HeLa and Vero cells were cultured in DMEM at 37 °C and 5% CO2. Cells were treated for 1 h with MPN at 10 and 100 µM, NM102 at 10 and 300 µM, NM102 nanoformulation at 1.29 and 5.16 mM or their respective control 10% DMSO or empty nanoformulation. Cytotoxicity was assessed using CellTiter96®AQueous. Values for treated cells were normalized to the untreated control. The results reported are mean ± SD of three independent experiments each in triplicates. B Mice were i.p. treated with NM102 (6 mg/kg) or control. Changes in the mice body weight were assessed for 7 days. Source data are provided as a source data file.