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. 2025 Apr 28;15:14894. doi: 10.1038/s41598-025-98576-x

Table 2.

Comparison of Sattler’s layer vessel metrics between acute and chronic CSC.

OCT-Angiography OCT-Strucure
Acute CSC Chronic CSC Acute CSC Chronic CSC
Metrics Mean SD Mean SD P-value Mean SD Mean SD P-value
Node numbers (n) 540.7 50.54 530.43 62.72 0.221 438.85 62.6 415.17 74.35 0.013*
Vessel area density (%) 46.77 2.41 46.87 2.55 0.886 48.2 1.61 48.13 1.58 0.498
Total vessel length (um) 168.99 8.77 167.99 11.66 0.356 137.06 12.24 132.41 12.24 0.023*
Vessel length density (%) 3.3 0.17 3.28 0.23 0.392 7.83 0.7 7.57 0.7 0.023
Vessel length density (mm-1) 6.76 0.35 6.72 0.47 0.356 5.48 0.49 5.3 0.49 0.023*
Mean length (um) 163.52 9.68 165.79 11.33 0.264 182.16 15.6 187.37 19.26 0.023*
Median length (um) 110.59 6.42 111.24 6.49 0.486 124.94 9.66 128.45 12.87 0.054
Lengths variation (um) 123666.4 38030.38 121460.8 43349.86 0.769 63614.62 21275.11 69026.8 25453.24 0.138
Lengths skew (um) 14.62 4.21 13.68 4.33 0.176 7.47 1.58 7.65 1.81 0.306
Lengths kurtosis (um) 302.06 155.28 269.58 153.26 0.160 84.59 33.42 90.77 40.57 0.26
Mean diameter (um) 87.78 3.98 89.73 4.99 0.020* 82.35 5.86 86.54 8.89 0.001*
Median diameter (um) 86.54 3.68 88.15 3.93 0.033* 75.9 4.9 78.61 6.13 0.003*
Diameter variation (um) 1726.58 204.33 1934.57 417.22 0.000* 1543.32 705.81 2110.85 1901.75 0.002*
Diameter skew (um) 0.37 0.1 0.43 0.17 0.019* 1.09 0.29 1.23 0.51 0.103
Diameter kurtosis (um) 3.21 0.24 3.35 0.44 0.219 4.98 1.45 5.67 3.27 0.211
Branchpoint density (nodes/mm) 3.2 0.23 3.15 0.26 0.285 3.19 0.28 3.12 0.37 0.040*
Fractional dimention 1.990 0.000 1.990 0.001 0.326 1.872 0.004 1.874 0.005 0.013*

CSC: central serous chorioretinopathy; SD: standard deviation.

* Statistically significant P-value.