Table 3.
Minimum inhibitory concentration (MIC) of α, β-unsaturated carbonyl compounds (3a-j) and their pyrazoline derivatives (4a-e and 5a-b) against fungi.
| Compounds | MIC (µg/mL) | ||
|---|---|---|---|
| Candida albicans (ATCC 90028) | Candida parapsilosis (ATCC 22019) | Candida tropicalis (ATCC 750) | |
| 3a | > 50 | > 50 | > 50 |
| 3b | 25 | 50 | 25 |
| 3c | > 50 | > 50 | > 50 |
| 3d | > 50 | > 50 | > 50 |
| 3e | > 50 | > 50 | > 50 |
| 3f | > 50 | > 50 | > 50 |
| 3g | > 50 | > 50 | > 50 |
| 3h | 6.25 | 12.5 | 12.5 |
| 3i | > 50 | > 50 | > 50 |
| 3j | 25 | 25 | 25 |
| 4a | > 50 | > 50 | > 50 |
| 4b | > 50 | > 50 | > 50 |
| 4c | 6.25 | 6.25 | 6.25 |
| 4d | > 50 | > 50 | > 50 |
| 4e | > 50 | > 50 | > 50 |
| 5a | > 50 | > 50 | > 50 |
| 5b | > 50 | > 50 | > 50 |
| Fluconazole | 0.25 | 2 | 1 |