Figure 2.
Metaphase and interphase fluorescence in situ hybridization (FISH) demonstrating IGH-PAX5 fusion in a splenic marginal zone lymphoma specimen with an abnormal karyotype (48,XY, + 3,t(9;14)(p13.2;q32), + 18cp). There are two yellow fusion signals (yellow arrows), indicating IGH-PAX5 fusion, in both the metaphase spread and the interphase nucleus.
