Table 3.
Associations between maternal plasma PFAS levels after delivery and inversely normalized measles VARscore during early childhood in 348 post-vaccination children, stratified by preterm status.
PFAS | Term Birth (N = 288) | Preterm Birth (N = 60) | P for interaction | ||
---|---|---|---|---|---|
Log2 transformed | Beta ± SE | P | Beta ± SE | P | PFAS × Preterm |
Me-PFOSA-AcOH | −0.07 ± 0.04 | 0.095 | −0.13 ± 0.09 | 0.136 | 0.316 |
PFDeA | 0.08 ± 0.05 | 0.114 | −0.24 ± 0.12 | 0.042 | 0.054 |
PFHpS | −0.07 ± 0.05 | 0.231 | −0.21 ± 0.09 | 0.028 | 0.189 |
PFHxS | −0.09 ± 0.04 | 0.032 | −0.15 ± 0.11 | 0.175 | 0.637 |
PFNA | 0.08 ± 0.07 | 0.233 | −0.08 ± 0.16 | 0.620 | 0.703 |
PFOA | −0.09 ± 0.06 | 0.163 | −0.09 ± 0.10 | 0.374 | 0.829 |
PFOS | −0.05 ± 0.06 | 0.390 | −0.34 ± 0.13 | 0.010 | 0.033 |
PFUnA | 0.02 ± 0.04 | 0.684 | −0.13 ± 0.08 | 0.146 | 0.256 |
PFAS burden score | −0.02 ± 0.09 | 0.811 | −0.33 ± 0.20 | 0.097 | 0.243 |
Adjusted for maternal race and ethnicity, maternal age at delivery, maternal smoking during pregnancy, delivery type, sex, breastfeeding pattern and years since last vaccination.