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Schematic diagram of MRI scans. A set of multiparametric MRI techniques was utilized, including fast spin echo (FSE) for assessing brain volume, phase-contrast (PC) for gCBF, pseudo-continuous arterial spin labeling (pCASL) for rCBF, T2-relaxation-under-spin-tagging (TRUST) for OEF, and diffusion-weighted imaging (DWI) for ADC. CMRO2 was calculated based on gCBF and OEF using the Fick principle.
