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. 2025 Apr 16;19:1595393. doi: 10.3389/fnins.2025.1595393

Table 2.

The basic characteristics of included studies on swallowing function intervention (n = 7).

Author Year of publication Research design Research setting DoC types Disease diagnosis Sample/cases Intervention method Swallowing function outcome
Implementer Intervention content Time
Control group Experimental group
Wu et al. (2016) 2016 Quasi-experiment China Coma Stroke 93 Nurse 4 1 — The swallowing frequency
Zhang et al. (2017) 2017 Experiment study China MCS Stroke/trauma 30 Physical therapist 1 + 2 1 + 2 + 3 Four weeks KDT
Jakobsen et al. (2019) 2019 Experiment study Denmark Coma Trauma 19 Physical therapist — 7 Three weeks PAS FOIS SEMG
Zhang C. H. et al. (2021) 2021 Quasi-experiment China Coma Stroke/trauma 60 Nurse /patient’s family 1 1 + 6 Four weeks MMASA
Zhang et al. (2023) 2023 Quasi-experiment China MCS Stroke/trauma 60 Physical therapist /nurse 1 + 2 + 3 1 + 2 + 3 Four weeks KDT
Theytaz et al. (2023) 2023 Quasi-experiment Swiss UWS MCS Stroke/trauma 28 Physical therapist 8 9 Eighteen months SEMG
Wang et al. (2023) 2023 Quasi-experiment China Coma — 63 Physical therapist 1 1 + 2 1 + 2 + 3 Four weeks KDT SSA

DoC, disorders of consciousness; MCS, minimally conscious state; UWS, unresponsive wakefulness syndrome; KDT, Kubota Drinking Test; PAS, Penetration Aspiration Score; FOIS, Functional Oral Intake Scale; MMASA, Modified Mann Assessment of Swallowing Ability; SEMG, Surface Electromyography; SSA, Standardized Swallowing Assessment; 1, sensory stimulation therapy; 2, neuromuscular electrical stimulation therapy; 3, K-point stimulation; 4, oromotor exercises; 5, facial oral tract therapy; 6, intermittent ora-esophageal tube feeding; 7, nonverbal facilitation of swallowing; 8, palpation; 9, Nox-T3 device; —, not be described.