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. 2025 Apr 16;12:1545095. doi: 10.3389/fmed.2025.1545095

Table 3.

Results of GO functional enrichment analysis.

GO term (name) Category Gene count P-value FDR-corrected value Enrichment ratio
Immune response BP 9 0.002 0.008 3.7
Inflammatory response BP 11 0.001 0.006 4.1
Cell migration BP 7 0.004 0.015 3.0
Cytokine activity MF 6 0.008 0.018 2.8
Regulation of T cell differentiation BP 8 0.003 0.011 3.3
Regulatory T cell differentiation BP 6 0.005 0.016 3.2
Plasma membrane CC 8 0.003 0.012 3.1
Protein binding MF 10 0.007 0.02 2.9
Regulation of cell proliferation BP 9 0.003 0.01 3.4
Extracellular matrix CC 5 0.009 0.022 2.7
Signal transduction BP 12 0.002 0.009 3.8
T cell activation BP 10 0.004 0.014 3.5
Cell surface CC 7 0.005 0.017 2.8
Enzyme activity regulation MF 8 0.006 0.018 3.1
Regulation of cellular secretion BP 9 0.003 0.011 3.3

GO enrichment analysis was conducted using the DAVID tool based on significantly differentially expressed genes. Significance was assessed using Fisher’s exact test, and results were corrected for multiple comparisons using the false discovery rate (FDR) method.