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. 2025 Apr 16;12:1545095. doi: 10.3389/fmed.2025.1545095

Table 4.

Immunohistochemistry (IHC) scoring results.

Gene name Mean score (patients) Mean score (controls) P-value Effect size (Cohen’s d)
IL1B 3.78 1.42 0.002 1.34
CCL17 4.12 1.58 0.001 1.45
POSTN 3.45 1.33 0.004 1.28
TNF 3.22 1.56 0.005 1.15
MUC5AC 4.33 1.47 0.001 1.52
ALOX5 3.68 1.65 0.003 1.22
IFNG 1.28 2.98 0.006 −1.05
FOXP3 1.42 3.22 0.004 −1.12
STAT4 1.12 3.11 0.003 −1.25
CXCL9 1.35 3.45 0.002 −1.38

Independent samples t-tests were used to evaluate significant differences between the patient and control groups, and Cohen’s d was calculated to assess the effect size. Significance was determined using P-values.