Figure 2.
CFU counts M. avium culture inside THP-1 cells treated with free forms of RIF and combination [R4W4]+RIF. (A) CFU/mL of M. avium treated with 4, 8, 16 µg/mL free RIF and with 4, 8, 16 µg/mL free RIF with 2, 4, 8 µg/mL [R4W4], respectively, at 3 h post-treatment. (B) CFU/mL of M. avium treated with 4, 8, 16 µg/mL free RIF and with 4, 8, 16 µg/mL free RIF with 2, 4, 8 µg/mL [R4W4], respectively, at 4 days post-treatment. (C) CFU/mL of M. avium treated with 4, 8, 16 µg/mL free RIF and with 4, 8, 16 µg/mL free RIF with 2, 4, 8 µg/mL [R4W4], respectively, at 8 days post-treatment. GraphPad Prism Software version 9.5.1 was utilized for analysis. Statistical analysis was performed using ANOVA. p-values are indicated at the top of each graph, and <0.05 (*) and <0.01 (**) were considered significant. ****=P value <0.0001.
