| 1. The clinical spectrum of SIBO range from
mild to moderate nonspecific gastrointestinal symptoms to
more severe clinical consequences, such as nutritional
deficiencies and weight loss. |
| 2. SIBO should be considered in the presence of
non-specific gastrointestinal symptoms and/or signs of
malabsorption, in the absence of another diagnosis on image
and endoscopy, especially in those with risk factors. |
| 3. Although less specific and sensitive breath
tests are the first line investigation due to it noninvasive
technique, low price and accessibility worldwide. |
| 4. Culture of small bowel aspirate is the gold
standard diagnostic method. However, it is invasive and
operator dependent (perfect technique). |
