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. 2025 May 1;23:254. doi: 10.1186/s12916-025-04058-2

Table 2.

The differently expressed proteins (DEPs) that were validated using immunohistochemistry (AHA IV/VI)

Protein name Accession Gene symbol FC
(discovery)
FC
(validation)
P-value
(discovery)
P-value
(validation)
Cell surface adhesion receptor 44 B9A6J2 CD44  − 1.6649  − 1.2924 4.95E − 03 0.0287
Galectin 1 A0A0B6XK00 GAL-1  − 1.2110  − 1.4311 4.66E − 05 0.0355
Triggering receptor expressed on myeloid cells 2 Q5TCX1 TREM2 2.3160 1.7664 7.06E − 05 0.0221
SMAD Family Member 3 A0A024R5Z3 SMAD3  − 2.4386  − 1.7348 1.73E − 10 0.1851
Interleukin 6 receptor A0A087 WTB5 IL-6R 2.0382 1.6389 4.66E − 06 0.0404