Table 3.
AUC, Sensitivity, specificity and youden index for EUS-UC score, MES, biomarkers and histological activity in patients with UC.
| AUC | CI | Cut-offs | Youden index | Sensitivity | Specificity | P-value | |
|---|---|---|---|---|---|---|---|
| MES | 0.766 | 0.662-0.869 | >1 | 0.4097 | 84.44% | 56.52% | <0.001 |
| EUS-UC score | 0.840 | 0.751-0.929 | >3 | 0.5382 | 75.56% | 78.26% | <0.01 |
| CRP | 0.692 | 0.569-0.815 | >2.5 | 0.4899 | 53.33% | 95.95% | <0.01 |
| albumin | 0.686 | 0.553-0.818 | ≤40 | 0.3420 | 73.33% | 60.87% | <0.01 |
| NLR | 0.571 | 0.429-0.713 | >2.37 | 0.2261 | 40.00% | 82.61% | 0.33 |
| ESR | 0.604 | 0.471-0.738 | >15 | 0.3585 | 48.89% | 86.96% | 0.36 |
| Truelove and Witt score | 0.713 | 0.578-0.848 | >0 | 0.3894 | 91.11% | 47.83% | <0.01 |
| combination | 0.880 | 0.801-0.959 | ─── | 0.6667 | 66.67% | 100.00% | <0.001 |
AUC, Area under the receiver operating characteristic curve; MES, Mayo endoscopic score; EUS-UC, Endoscopic Ultrasound-Ulcerative Colitis score, CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; NLR, neutrophil-to-lymphocyte ratio; CI, confidence interval.