Table 3.
Linear mixed effect model for change in serum IgG level between two visits during RTX/OCR in the two cohorts.
|
Predictors |
Change in serum IgG level between two visits |
||
|---|---|---|---|
| Estimates | CI | p | |
| (Intercept) | 1.10 | 0.76–1.44 | <0.001 |
| Serum IgG level at RTX/OCR initiation | −0.12 | −0.14–−0.10 | <0.001 |
| Delay since last RTX/OCR infusion | 0.01 | 0.00–0.02 | 0.003 |
| Age | −0.00 | −0.01–0.00 | 0.398 |
| Sex [M] | −0.05 | −0.18–0.07 | 0.408 |
| Immunosuppressive (IS) DMT prior to RTX/OCR initiation | −0.08 | −0.23–0.06 | 0.255 |
DMT: disease modifying therapy; immunosuppressive DMT included all DMTs for multiple sclerosis except platform therapies.