Table 3.

List of circRNA-miRNA involved in early stages and EMT of BC. All information (Model of study, circRNA, pattern, target miRNA, and respective target mRNA) in each row was obtained from the reference cited. Each row would thus present a circRNA/miRNA/mRNA axis. A maximum of 4 miRNA/mRNA targets were included in the respectively referenced paper in each row, with the full list in the original paper. Each circRNA was written as cited in its respective research paper. CircRNAs nomenclature varies between ID, Alias, chromosomal position, or referring to its parental gene. The rows are referred to as numbered from 1–13. (-) indicates that this information wasn’t available in the reference data

Model of study	Cancer Stage	CircRNA	Pattern	Reference	Target miRNA	Target mRNA
Human breast tissue	Stage I-IIA cancer	hsa_circ_0023990	Up	[86]	hsa‐miR‐548b‐3p	SLCO6A1 FAT2 CD46
	Stage I-IIA cancer	hsa_circ_0016601	Up	[86]	hsa‐miR‐1246	SKIL
	Stage I-IIA cancer	hsa_circ_0001946	Up	[86]	hsa‐miR‐1299	FSD2 OCA2 CCND1 MYRF
	Stage I-IIA cancer	hsa_circ_0000117	Up	[86]	hsa‐miR‐502‐5p	APOB
	Early cancer stages	hsa_circ_0005046	Up	[87]	hsa-miR-215	AKT1
	Early cancer stages	hsa_circ_0001791	Up	[87]	hsa-miR-383 hsa-miR-1236 hsa-miR-1244	-
Human epithelial cell line	Pre-tumorigenic/early cancer	hsa_circ_0077755	Down	[88]	miR-182	-
	EMT	circSCYL2	Down	[89]	hsa-miR-6804-5p hsa-miR-1270 hsa-miR-6824-5p hsa-miR-4308	FKBP1B ADAMTS1 MDGA2 HSF5
	EMT	circANKRD12	Down	[89]	hsa-miR-6721-5p hsa-miR-6849-5p hsa-miR-6889-3p hsa-miR-6514-5p	SGSM1 FRAT1 ERG WNT11
	EMT	circMYO9A	Down	[89]	hsa-miR-222-3p hsa-miR-5006-5p hsa-miR-6796-5p hsa-miR-6511a-5p	CSF1 TRAF3 RELB CASP10
TNBC tissue	EMT	circANKS1B	Up	[90]	miR-152-3p miR-148a-3p	USF1 ESRP1
TCGA samples and human epithelial cell line	EMT	circNCAPG	Up	[91]	miR-200c miR-200b	CSF-1 ZEB-1
Human breast tissue	EMT	circRNA_000554	Down	[92]	miR-182	ZFP36