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. 2025 May 2;15:15453. doi: 10.1038/s41598-025-99857-1

Table 2.

Comparison of FOT values between non-IPF ILDs and IPFs.

All patients
N = 160
Stable non-IPF ILDs
n = 139
IPF
n = 21

Rrs5 Inspiratory

(cmH2O/(L/sec))

0.38 (-0.35–1.18) 0.33 (-0.28–1.25) 0.41 (-0.64–1.15)
Rrs5 Inspiratory (%pred) 111 (91–139) 109 (93–142) 112 (84–137)

Rrs5 Expiratory

(cmH2O/(L/sec))

1.01 (0.08–1.75) 0.98 (0.2–1.75) 0.84 (-0.34–1.8)
Rrs5 Expiratory (%pred) 132 (104–163) 131 (105–161) 126 (93–166)

Rrs5 Whole breath

(cmH2O/(L/sec))

0.71 (0.05–1.57) 0.7 (0.17–1.58) 0.49 (-0.4–1.57)
Rrs5 Whole breath (%pred) 122 (100–154) 122 (105–155) 115 (89–154)
Xrs5 Inspiratory (cmH2O/(L/sec)) -0.01 (-1.2–0.8) 0.31 (-0.61–0.99) -0.39 (-1.42–0.53)*
Xrs5 Inspiratory (%pred) 100 (73–141) 91 (67–121) 115 (82–149)*
Xrs5 Expiratory (cmH2O/(L/sec)) -0.1 (-1.96–1.01) 0.24 (-2.17–1.14) -0.23 (-1.69–0.97)
Xrs5 Expiratory (%pred) 101 (66–179) 90 (61–182) 106 (67–179)
Xrs5 Whole breath(cmH2O/(L/sec)) -0.08 (-1.89–0.8) 0.13 (-1.4–1.07) -0.52 (-2.12–0.78)
Xrs5 Whole breath (%pred) 103 (71–170) 96 (63–151) 116 (74–170)

Continuous variables are expressed as median (interquartile ranges).

*p-value < 0,05 comparing stable ILDs to PPFs.

FOT forced oscillation technique, ILD interstitial lung disease, PPF progressive pulmonary fibrosis, Rrs5 respiratory system resistance at 5Hz, Xrs5 respiratory system reactance at 5Hz, cmH2O/(L/sec) centimeter of water per liter per second