Table 1.
Hepatic antioxidant defense system and oxidative stress indicators (LPO) in Nile tilapia exposed to AgNO3 and various doses of AgNPs over a two-week period.
Control | AgNo3 | AgNPs 10 | AgNPs 20 | AgNPs 50 | AgNPs 100 | |
---|---|---|---|---|---|---|
SOD (U/g) | 51.8 ± 4.4a | 61.7 ± 5.2b | 58.3 ± 3.8abc | 59.6 ± 4.6abc | 62.2 ± 5.1bc | 71.5 ± 4.3 |
CAT (U/g) | 72.3 ± 3.7 | 83.4 ± 4.1b | 76.3 ± 3.2b | 79.8 ± 4.5b | 92.4 ± 4.2c | 98.2 ± 4.2c |
GPx (U/g) | 61.5 ± 3.4 | 77.6 ± 4.2b | 71.1 ± 3.1b | 77.9 ± 4.9b | 81.2 ± 4.3b | 90.7 ± 5.1 |
GR (U/g) | 0.75 ± 0.3 | 1.32 ± 0.2b | 1.07 ± 0.2b | 1.23 ± 0.3b | 1.93 ± 0.3d | 2.16 ± 0.2d |
LPO (nM/mg) | 1.50 ± 0.2 | 2.31 ± 0.2b | 2.13 ± 0.3b | 2.30 ± 0.3b | 2.56 ± 0.3bc | 2.75 ± 0.2c |
TAC (mM/mg) | 3.57 ± 0.3 | 3.31 ± 0.2b | 3.10 ± 0.5bc | 3.13 ± 0.4 c | 2.81 ± 0.5cd | 2.55 ± 0.3d |
Data within a row with similar superscripts have no significant difference between them (Tukey Test, P < 0.05). Data were expressed as mean ± S.D. data (n = 6 fish).
SOD superoxide dismutase, CAT catalase, GPx glutathione peroxidase, GR glutathione reductase, LPO lipid peroxidase, TAC total antioxidant capacity.