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. 2025 May 2;15:15390. doi: 10.1038/s41598-025-97731-8

Table 1.

Hepatic antioxidant defense system and oxidative stress indicators (LPO) in Nile tilapia exposed to AgNO3 and various doses of AgNPs over a two-week period.

Control AgNo3 AgNPs 10 AgNPs 20 AgNPs 50 AgNPs 100
SOD (U/g) 51.8 ± 4.4a 61.7 ± 5.2b 58.3 ± 3.8abc 59.6 ± 4.6abc 62.2 ± 5.1bc 71.5 ± 4.3
CAT (U/g) 72.3 ± 3.7 83.4 ± 4.1b 76.3 ± 3.2b 79.8 ± 4.5b 92.4 ± 4.2c 98.2 ± 4.2c
GPx (U/g) 61.5 ± 3.4 77.6 ± 4.2b 71.1 ± 3.1b 77.9 ± 4.9b 81.2 ± 4.3b 90.7 ± 5.1
GR (U/g) 0.75 ± 0.3 1.32 ± 0.2b 1.07 ± 0.2b 1.23 ± 0.3b 1.93 ± 0.3d 2.16 ± 0.2d
LPO (nM/mg) 1.50 ± 0.2 2.31 ± 0.2b 2.13 ± 0.3b 2.30 ± 0.3b 2.56 ± 0.3bc 2.75 ± 0.2c
TAC (mM/mg) 3.57 ± 0.3 3.31 ± 0.2b 3.10 ± 0.5bc 3.13 ± 0.4 c 2.81 ± 0.5cd 2.55 ± 0.3d

Data within a row with similar superscripts have no significant difference between them (Tukey Test, P < 0.05). Data were expressed as mean ± S.D. data (n = 6 fish).

SOD superoxide dismutase, CAT catalase, GPx glutathione peroxidase, GR glutathione reductase, LPO lipid peroxidase, TAC total antioxidant capacity.