Table 2.
Hepatic antioxidant defense system and oxidative stress indicators (LPO) in Nile tilapia exposed to AgNO3 and various doses of AgNPs over a four-week period.
| Control | AgNo3 | AgNPs 10 | AgNPs 20 | AgNPs 50 | AgNPs 100 | |
|---|---|---|---|---|---|---|
| SOD (U/g) | 50.1 ± 4.2 | 63.4 ± 5.1b | 61.8 ± 4.6bc | 65.4 ± 4.2bc | 67.8 ± 4.9c | 74.1 ± 4.2 |
| CAT (U/g) | 74.2 ± 4.1 | 85.2 ± 4.3b | 81.8 ± 3.8b | 83.5 ± 3.4b | 95.5 ± 4.9c | 102.5 ± 6.7c |
| GPx (U/g) | 59.2 ± 3.8 | 78.1 ± 2.7 | 73.4 ± 3.6b | 69.8 ± 3.1b | 63.7 ± 2.7b | 68.9 ± 3.8b |
| GR (U/g) | 0.76 ± 0.2a | 1.93 ± 0.2 | 1.28 ± 0.1b | 1.32 ± 0.2b | 1.15 ± 0.2b | 0.72 ± 0.3a |
| LPO (nM/mg) | 1.38 ± 0.2 | 2.66 ± 0.3b | 2.31 ± 0.2bc | 2.41 ± 0.3bc | 3.34 ± 0.3d | 3.26 ± 0.2d |
| TAC (mM/mg) | 3.46 ± 0.3 | 2.61 ± 0.1b | 2.51 ± 0.2bc | 2.33 ± 0.2bcd | 2.71 ± 0.2bc | 2.32 ± 0.1bd |
Data within a row with similar superscripts have no significant difference between them (Tukey Test, P < 0.05). Data were expressed as mean ± S.D. data (n = 6 fish).
SOD superoxide dismutase, CAT catalase, GPx glutathione peroxidase, GR glutathione reductase, LPO lipid peroxidase, TAC total antioxidant capacity.