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. 2025 Mar 17;44(9):2658–2694. doi: 10.1038/s44318-025-00407-2

Reagents and tools table

Reagent/Resource Reference or Source Identifier or Catalog Number
Experimental models
hTERT-RPE-1 cells ATCC CRL-4000
Recombinant DNA
N/A
Antibodies
Alexa Fluor® 647 anti-histone H3 (phospho S10) Abcam ab196698
Rabbit polyclonal Anti-phospho-Histone H3 (Ser10) Abcam ab5176
Mouse anti-rabbit IgG-HRP Santa Cruz sc-2357
Rabbit polyclonal to beta Tubulin Abcam ab6046
m-IgGκ BP-HRP Santa Cruz sc-516102
cyclin B1 (GNS1) mouse monoclonal IgG1 Santa Cruz sc-245
Anti-RPB1 CTD(S5P) Abcam ab5131
Anti-RPB1 CTD(S2P) Abcam ab5095
Oligonucleotides and other sequence-based reagents
N/A
Chemicals, Enzymes and other reagents
Chemicals
4′,6-diamidino-2-phenylindole (DAPI) TFS D1306
Dimethyl sulfoxide (DMSO) Sigma 472301
DMEM/F-12 with GlutaMAX Gibco/TFS 10565-018
Fetal bovine serum Sigma F9665
Glycine Bio-Rad 1610718
MG132 Merck M7449-1ML
Nocodazole Merck SML1665-1ML
Palbociclib Selleckchem S1116
Paraformaldehyde EMS 15714
Penicillin-streptomycin Gibco 15140-122
Phosphate-buffered saline (PBS) Vivantis PB0344-1L
PBS-T (PBS + 0.1% Tween 20) Sinopharm T20087687
Prolong Gold antifade reagent TFS P36930
Taxol Santa Cruz 33069-62-4
Triton X-100 Alfa Aesar A16046
Chromatin
HeLa oligonucleosomes EpiCypher 16-0003
Software
Adobe Illustrator Adobe
Adobe Photoshop Adobe
Adobe Premiere Pro Adobe
Auxiliary scripts Gan lab, github.com/anaphaze/ot-tools
BioRender BioRender
Bsoft lsbr.niams.nih.gov/bsoft (Heymann and Belnap, 2007)
cryo-CARE github.com/juglab/cryoCARE_pip (Buchholz et al, 2019)
EMAN2 blake.bcm.edu/emanwiki/EMAN2 (Chen et al, 2017)
FIJI imagej.net/software/fiji (Schindelin et al, 2012)
Google sheets Google
IMOD bio3d.colorado.edu/imod (Mastronarde, 1997)
PEET bio3d.colorado.edu/PEET (Nicastro et al, 2006)
RELION github.com/3dem/relion (Scheres, 2012)
SerialEM bio3d.colorado.edu/SerialEM (Mastronarde, 2005)
UCSF Chimera www.cgl.ucsf.edu/chimera (Pettersen et al, 2004)
Other
Light microscopy
LSM900 AiryScan microscope Zeiss N/A
20×, 0.8 N.A. Plan-Apochromat Zeiss N/A
63×, 1.4 N.A. oil Plan-Apochromat Zeiss N/A
ZEN 3.0 (blue edition) Zeiss N/A
Eclipse Ti microscope Nikon N/A
Plan Fluor 10x Ph1 objective Nikon N/A
20 mm Ø coverslip Paul Marienfeld GmbH 0112600
Electron cryomicroscopy
C-flat 2/4 200 mesh, gold Protochips CF-2/4-2Au
C-Clip Ring (autogrid) TFS 1036173
CryoFIB autogrid TFS 1205101
C-flat 2/4 200 mesh, copper Protochips CF-2/4-2C
Continuous carbon EMS CF200-Cu-UL
Whatman Grade 1 filter paper Whatman 1001-055
Copper tubes, 0.3 mm inner diameter Wohlwend N/A
Copper tube loading tool Wohlwend Part 733-1
Copper tube cutting device Wohlwend Part 732
UC7/FC7 Microtome Leica N/A
35° diamond knife Diatome Cryo35
Micromanipulator, Leica Leica N/A
Micromanipulator, MN-151-S Narishige N/A
Vitrobot Mark IV TFS N/A
Helios Nanolab 650 FIB-SEM TFS N/A
PolarPrep 2000 Cryo Transfer System Quorum N/A
Titan Krios G1 cryo-TEM TFS N/A
Falcon II camera TFS N/A
Gatan K3 Summit camera AMETEK N/A
Gatan BioContinuum imaging filter AMETEK N/A