Figure 1.

Potential pathogens detected by mNGS and CTM. Fungi and viruses were the most frequently detected pathogens, followed by G− and G+ bacteria. The bar graph shows the number of cases in which each pathogen was detected out of the 63 infection episodes. Pathogens are categorized into three groups: identical detection (green): pathogens detected by both mNGS and CTM; extra detection (red): pathogens detected exclusively by either mNGS or CTM, with pathogenicity not ruled out; and false-positive detection (blue): microorganisms detected by either mNGS or CTM but clinically diagnosed as non-causative pathogens. CMV: cytomegalovirus; EBV: Epstein-Barr virus; HSV: herpes simplex virus; HHV: human herpes virus.