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. 2025 May 3;26:439. doi: 10.1186/s12891-025-08698-6

Table 1.

Clinical baseline characteristics of the primary TKA patients

Baseline characters Total (n = 1444) LHBL (n = 1208) HHBL (n = 236) p-value
Age (years) 67.0 (63.0, 71.0) 67.0 (63.0, 71.0) 67.5 (63.0, 71.0) 0.621a
Female (n, %) 1097 (75.9) 925 (76.6) 172 (72.9) 0.225b
BMI (kg/m2) 27.1 (25.0 29.5) 27.1 (25.0, 29.6) 27.2 (24.8, 29.4) 0.654a
Smoking (n, %) 95 (6.6) 79 (6.5) 16 (6.8) 0.892b
Alcohol drinking (n, %) 98 (6.8) 82 (6.8) 16 (6.8) 0.996b
Comorbidity history (n, %)
 Hypertension 799 (0.55) 661 (54.7) 138 (58.5) 0.288b
 Diabetes 269 (18.6) 226 (18.7) 43 (18.2) 0.860b
 Cerebral infarction 89 (6.2) 75 (6.2) 14 (5.9) 0.343b
 CAD 149 (10.3) 113 (9.4) 36 (15.3) 0.006b*
 Atrial fibrillation 16 (1.1) 13 (1.1) 3 (1.3) 0.736c
 Renal disease 25 (1.7) 22 (1.8) 3 (1.3) 0.785c
 Liver disease 15 (1.0) 12 (1.0) 3 1.3) 0.723c
 Varicose Veins in the Legs 113 (7.8) 98 (8.1) 15 (6.4) 0.358b
 Preoperative DVT 51 (3.5) 40 (3.3) 10 (4.2) 0.478b
 Preoperative anticoagulant (n, %) 178 (12.3) 140 (11.6) 38 (16.1) 0.054b
 Preoperative EPO (n, %) 186 (19.8) 264 (21.9) 22 (9.3)  < 0.001b

LHBL low hidden blood loss group, HHBL high hidden blood loss group, BMI body mass index, CAD coronary artery disease, DVT deep venous thrombosis, EPO erythropoietin

aMann-Whitney U-test

bPearson’s chi-square test

cFisher’s exact test