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. 2025 May 3;26:439. doi: 10.1186/s12891-025-08698-6

Table 5.

Backwards stepwise binary logistic regression of the risk factors for HBL in patients with knee osteoarthritis involvement undergoing TKA

Characteristic Univariable Multivariable
OR (95% CI) p-value OR (95% CI) p-value
CAD 1.74 (1.16 to 2.61) 0.007 1.72 (1.12 to 2.63) 0.013
WBC (× 109/L) 0.91 (0.82 to 1.00) 0.039 - 0.582
Hct (L/L) 83.28 (2.05 to 3389.10) 0.019 - 0.449
Hb (g/L) 1.02 (1.01 to 1.03) 0.004 - 0.308
PLT (× 109/L) 0.99 (0.99 to 1.00)  < 0.001 0.99 (0.99 to 1.00)  < 0.001
D-dimer (μg/mL) 0.76 (0.61 to 0.94) 0.011 0.81 (0.66 to 1.00) 0.057
Left knee/right knee 1.45 (1.10 to 1.92) 0.009 1.44 (1.07 to 1.93) 0.015
CMTKA/RTKA 3.61 (2.13 to 6.10)  < 0.001 4.48 (2.56 to 7.83)  < 0.001
Operation time (min) 1.01 (1.00 to 1.01)  < 0.001 1.01 (1.01 to 1.02)  < 0.001
IBL > 20% 1.68 (1.18 to 2.40) 0.004 0.306
EPO prescription - -
 No prescription - - - -
 Preoperation 0.38 (0.23 to 0.60)  < 0.001 0.41 (0.25 to 0.67)  < 0.001
 Postoperation 1.07 (0.78 to 1.48) 0.665 1.20 (0.85 to 1.68) 0.295

CAD coronary artery disease, TKA total arthroplasty, OR odd ratios, CI confidence interval, WBC white blood cell count, Hct hematocrit, Hb hemoglobin, PLT platelet, CMTKA conventional manual total knee arthroplasty, RTKA robotic-assisted total knee arthroplasty, IBL Intraoperative blood loss, EPO erythropoietin