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. 2025 May 5;86(3):e70099. doi: 10.1002/ddr.70099

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© 2025 The Author(s). Drug Development Research published by Wiley Periodicals LLC.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Inhibition of the biosynthesis of 5‐LO products by Zil (3), CAPE (1) and OB‐CAPE (5) (1 μM) in HEK293 cells transfected with 5‐LO/FLAP. Values are the means ± SD of three independent experiments, each performed in duplicate. The graph shows values that are normalized to diluent (DMSO) controls. Values without at least one common superscript letter are significantly different (p < 0.05) as determined by two‐way ANOVA of the non‐normalized data with subsequent Tukey's multiple comparisons test.