Abstract
Purpose
There has been a consistent upward trend in orthodontic treatment across all age groups. It is one of the longest and most common medical interventions for children. There is a growing interest in the connection between orthodontic treatment and children’s oral health-related quality of life to provide an insight into treatment needs and outcomes, as well as long-term improvement in oral health. However, to our knowledge the impact of fixed orthodontic appliances on the mental health of the children, their social context and their families have not been sufficiently investigated and have not yet been summarized. The objectives were to provide an overview of empirical research regarding the impact of fixed orthodontic appliances on children’s mental health, social context and families.
Patients and Methods
A comprehensive literature search was conducted across four databases. Studies investigating the effects and impact of fixed appliances on mental health, social context and families of children up to the age of 18 were included. Data were extracted by two independent reviewers. The studies were reviewed, their results compared and analyzed narratively.
Results
Ultimately, 30 studies were analyzed. The most common conclusions were that oral health-related quality of life worsens during and improves again after treatment. The extent to which orthodontic treatment limits or affects children’s lives, their mental health, personality, personal development and behavior has not been extensively investigated.
Conclusion
Evidence of the impact of fixed orthodontic appliances on mental health and social context of children and their families is basically missing. However, this would be crucial for the consideration of evidence-based recommendations. Therefore, the impact of fixed orthodontic appliances should be addressed in further empirical studies.
Keywords: fixed orthodontic appliances, children, mental health, social context, orthodontics, oral health-related quality of life, scoping review
Introduction
Orthodontics involves the preventive and corrective treatment of functional disorders and malocclusions of the teeth and jaws.1 Within orthodontics, the treatment with fixed orthodontic appliances, is a regular occurrence to correct malocclusions.2
The Children’s Dental Health Survey conducted in 2013, showed that 3%, 21% and 16% of 8-, 12- and 15-year-old British children were under orthodontic treatment.3 Between the ages of three and seventeen, 21% of all boys and 26% of all girls undergo continuous orthodontic treatment in Germany.4 The utilization of orthodontic services peaks among 13-year-old girls (55%) and 14-year-old boys (51%). Orthodontic treatment ranks among the longest and most common medical interventions for children, with an average treatment duration of three to four years.5
Over many decades, dental research was predominantly focused on clinically-oriented outcome measures.6 However, there has been a paradigm shift towards more patient-centered orthodontic treatment and the assessment of oral health-related quality of life (OHRQoL) has become more important.7 OHRQoL is a comprehensive concept that is significantly influenced by various factors such as mental health, social relationships and environment and it describes the effects of orofacial diseases and dental interventions as perceived by patients.8 Studies examining OHRQoL in orthodontics are important to provide an insight into treatment needs and outcomes, as well as long-term improvement in oral health.9 There is a growing interest in exploring the relationship between orthodontic treatment and OHRQoL.7 It is already known, that there is a deterioration in OHRQoL during orthodontic treatment, particularly in the early stages of treatment.10,11 Pain, difficulty eating, change of speech, and diet changes affect the OHRQoL during orthodontic treatment.12 Since the concept of OHRQoL is influenced by various factors, it is conceivable that children’s mental health or social relationships are also influenced by orthodontic treatment. Especially because orthodontic treatment lasts several years and mainly takes place during puberty, a time of major physiological and psychosocial changes and profound socio-emotional development.13,14 Additionally, orthodontic appliances are foreign objects inserted into a sensitive area of the body, causing physical and psychological discomfort.15 Patients’ psychological responses to orthodontic treatment are clearly a very significant concern.
However, most studies focus on the influence of orthodontic appliances on OHRQoL and do not consider a large number of other variables related to patients’ physical and psychological well-being.16 Particularly, the impact on mental health, families and social context of children wearing fixed orthodontic appliances has been inadequately investigated and have not been comprehensively summarized. In order to gain insights into this topic and to investigating the consequences of wearing orthodontic appliances, it is essential to investigate the relationship between treatment with fixed orthodontic appliances and the mental health, social context and family of children. Therefore, this scoping review aims to provide an overview of studies investigating mental health and the role of social context on children, including their families and peers while wearing fixed orthodontic appliances and to identify areas for a future agenda.
Materials and Methods
This scoping review was conducted in accordance with the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for Scoping Reviews) guidelines and the corresponding checklist.17 This scoping review was also conducted in accordance with the Joanna Briggs Institute (JBI) methodology for scoping reviews.
Inclusion and Exclusion Criteria and Search Strategy
At the beginning, the inclusion and exclusion criteria were defined based on the research question and the PICOS scheme. Studies investigating the effects and impact of fixed appliances on mental health, social context and families of children up to the age of 18 were included. All inclusion and exclusion criteria are outlined in Table 1.
Table 1.
PICOS Scheme, Inclusion and Exclusion Criteria
| PICOS | Inclusion Criteria | Exclusion Criteria |
|---|---|---|
| Population |
|
|
| Intervention |
|
|
| Control |
|
|
| Outcome |
|
|
| Setting |
|
These search terms were generated through brainstorming sessions, conducting keyword searches and analyzing MeSH terms in databases. The various search terms were assessed for applicability, revised and/or removed from the search. In this way, the search strategy was continuously refined in an iterative procedure until its final version. The final search strategies are presented in Table 2.
Table 2.
Search Strategies
| Database | Search Strategies | Results |
|---|---|---|
| MEDLINE via PubMed | ((“child*”) OR (“teen*”) OR (“adolesc*”) OR (“adolescent”[Mesh]) OR (“child”[Mesh])) AND ((“orthodontic*”) OR (“orthodontics”[Mesh])) AND ((“family relations”) OR (“social environment”) OR (“social behavior*”) OR (“self concept”) OR (“quality of life”) OR (“social perception”) OR (“social support”) OR (“mental health”) OR (“social environment”[Mesh]) OR (“social behavior*”[Mesh]) OR (“quality of life”[Mesh]) OR (“self concept”[Mesh]) OR (“family relations”[Mesh]) OR (“mental health”[Mesh]) OR (“Social Perception”[Mesh]) OR (“Social Perception”)) | 1531 |
| Web of Science | ALL=((“child” OR “teenager” OR “adolescent”) AND (“orthodontics” OR “orthodontic appliances” OR “orthodontic treatment”) AND (“family relations” OR “social environment” OR “social behavior” OR “self concept” OR “quality of life” OR “psychological well-being” OR “social perception” OR “social support” OR “mental health” OR “Social Perception” OR “psychological well-being” OR “oral health-related quality of life” OR “oral health” OR “peer support” OR “family support”)) | 337 |
| CINAHL | (“child” OR “teenager” OR “adolescent”) AND (“orthodontics” OR “orthodontic appliances” OR “orthodontic treatment”) AND (“family relations” OR “social environment” OR “social behavior” OR “self concept” OR “quality of life” OR “psychological well-being” OR “social perception” OR “social support” OR “mental health” OR “Social Perception” OR “psychological well-being” OR “oral health-related quality of life” OR “oral health” OR “peer support” OR “family support”) | 234 |
| Base | (“child” OR “teenager” OR “adolescent”) AND (“orthodontic appliances” OR “orthodontic treatment”) AND (“family relations” OR “social environment” OR “social behavior” OR “self concept” OR “quality of life” OR “psychological well-being” OR “social perception” OR “social support” OR “mental health” OR “Social Perception” OR “psychological well-being” OR “oral health-related quality of life” OR “oral health” OR “peer support” OR “family support”) | 523 |
Screening and Study Selection
A comprehensive and specific literature search was conducted in July 2023 and February 2024 in the electronic databases MEDLINE via PubMed, Web of Science, CINAHL und BASE. The last search day was February 15, 2024. In addition, a manual search was carried out. In addition, experts in this field were contacted. Title, abstract and full text screening was performed by two independent researchers. Any conflicts that arose were resolved through discussion with a third researcher, who acted as an independent supervisor.
Data Extraction
Given the heterogeneity of the publications included regarding design and method, the screeners proceeded to extract data from the articles included using a modified version of the Cochrane Data Collection Form for Intervention Reviews: randomized controlled trials (RCTs) and non-RCTs (Version 3). This was followed by a narrative synthesis of the main findings. The studies and their results were categorized using an inductive approach. In accordance with the JBI methodology, no formal assessment of the methodological quality of the studies included was undertaken.18
Results
Paper Selection
The database searches identified a total of 2625 publications. Among these, 755 duplicates were removed. Therefore, titles and abstracts of 1870 publications were screened. Based on the inclusion and exclusion criteria, full texts of 71 publications were reviewed. Of these, 26 articles were included in this review. Additionally, manual searches resulted in the inclusion of four further studies. This resulted in a total of 30 studies for the data analysis. The search and selection results are reported in the “Preferred Reporting Items for Systematic Reviews and Meta-analyses” (PRISMA) flow diagram (Figure 1).
Figure 1.
PRISMA Flow Diagram.
Characteristics of the Included Studies
Study details are shown in the data extraction table (Supplementary Table 1). The studies were published between 1994 and 2023 and included a total of 7.834 patients aged 11–18 years. Further study characteristics are shown in Table 3.
Table 3.
Study Characteristics
| Country | N* | Study Design | N* |
|---|---|---|---|
| Belgium | 1 | (observational) prospective cohort studies | 9 |
| Brazil | 11 | Population-based case-control study | 1 |
| Canada | 1 | Prospective studies | 3 |
| China | 4 | Follow-up study | 1 |
| Germany | 1 | Qualitative studies qualitative studies | 3 |
| India | 2 | (prospective) (controlled) longitudinal studies | 6 |
| Iran | 1 | Cross-sectional studies | 5 |
| Mexico | 1 | Descriptive study | 1 |
| Pakistan | 1 | Controlled randomized study | 1 |
| United Kingdom | 6 | ||
| United States | 1 |
Note: *Quantity.
Study Objectives, Outcome-Parameters and Assessments
The majority of the publications investigated the impact, or effects caused by fixed orthodontic appliance treatment on OHRQoL6,19–32 or overall quality of life.32–36 Some studies explored children’s perspectives of fixed orthodontic appliances treatment.37–39 Two studies examined the relationship between pain and OHRQoL.36,40 Other studies investigated the intensity and extent of impairment of daily life.41,42 One study assessed the effect of orthodontic appliances treatment on the families of adolescents.21,28,35 To measure the achievement of the study objectives, various assessments were used. All assessments relevant to the research question are presented in Supplementary Table 2.
Impact of Orthodontic Appliances on Children’s Oral Health-Related Quality of Life
One of the most common findings was that children with fixed orthodontic appliances had a greater chance of displaying negative impact on OHRQoL than those in the control or waiting group.23,25–29 More concretely, the results showed more frequent impact on the functional limitation, emotional well-being and social well-being of children wearing orthodontic appliances compared to those not undergoing treatment. OHRQoL is reported to be worse during treatment22,23,25,27–33,38 which may suggest that treatment has an impact on oral health and affects the (oral health-related) quality of life.6,16,19,24,27,30,43
During the course of treatment, the most significant changes in OHRQoL appear within the first month of treatment.22,24,27 During the initial phase of treatment, the level of OHRQoL usually decreased.27,38 OHRQoL could gradually improve during treatment.25,30,34,36,37 An improvement in OHRQoL after patients completed treatment, compared to the time (before or) during treatment was also demonstrated.6,19,20,24,25
Study results suggest that patients who had orthodontic appliance treatment had better OHRQoL at the follow-up compared to the control group.25,26,32
In terms of OHRQoL, pain was the most frequently reported impact on life as a result of orthodontic appliance treatment.6,23–25,31,38,39,41,42 There was a significant correlation between pain and quality of life.38,42 Patients reported moderate to severe pain42 and increased pain within the first week after insertion,24 followed by a gradual decrease.31,35,44 An increase in oral symptoms and functional limitations during treatment was also found.27,31,38 Marques et al16 and Abreu et al37 found no significant changes in oral symptoms and functional limitations.
Further influencing factors were: (psychological) discomfort, trauma, feeling of oral constraint, mouth sores, ulceration, shyness, anxiety, embarrassment, difficulty in relaxing, physical disability, impaired speaking, swallowing, difficulty biting and smiling.22–25,27,35,38,41–44
Impact of Orthodontic Appliances on Children’s Mental Health
An improvement in emotional and social well-being in the first month of treatment as well as 6 and 12 months after placement was identified.34,37 An improvement during and after treatment was also found.22,27 There was also an improvement in self-confidence, self-esteem and social interactions.40 They felt more comfortable, though less about their teeth, and were more confident when they smiled. Adolescents report improvements in dental self-confidence, dental appearance and a greater reduction in esthetic concerns.33
In contrast, children also reported a lack of confidence in public24,44 and experienced anxiety and embarrassment38 due to their fixed orthodontic appliance. Social well-being domains and self-esteem deteriorate during treatment.20,32 Deng et al33 reported no benefit of general psychological well-being after treatment and observed no significant pre-treatment to posttreatment change in patients’ self-esteem and body image. Corradi-Dias et al45 identified the most negative repercussions in the domains of physical impact and social impact during 6 months of fixed appliance treatment.
Impact of Orthodontic Appliance Treatment on the Social Context and Family
One study investigated the effect of orthodontic appliance treatment on the families.21 The results show an improvement in the overall QoL of families during treatment. Significant differences were observed compared to the control group over the study period in parental/family activity, parental emotions and the overall Family Impact Scale. The results showed a highly beneficial effect of orthodontic appliance treatment on the families of adolescents, with the families’ overall quality of life improving.
Discussion
Principal Findings
This scoping review provides a comprehensive overview of the impact of orthodontic appliance treatment on children’s mental health, their families and social context. Most studies investigated the impact of orthodontic appliance treatment on OHRQoL. The prevailing findings indicated a deterioration in OHRQoL during treatment and an improved OHRQoL following treatment.
Some studies reported an improvement in emotional well-being during treatment.19,22,27,30,35 One reason might be that orthodontic appliances become increasingly popular, are more widely accepted and society, especially peer groups, become accustomed to such appliances and adolescents feel more comfortable with their oral functions, resulting in rapid adaptation.19,23,27,35,39,41,45,46
However, study results on the social acceptance of fixed appliances vary. Patel et al47 found that children do not make social judgements about other children purely on the basis of wearing a fixed orthodontic appliance. Another study showed, that some children were often teased and annoyed because of their appliance.48
In addition, some teens were aware of and prepared for the pain and discomfort of the appliances prior to treatment, due to instructions by the orthodontist.30,36,39 In addition, the sensation of pain decreases as patients become accustomed to the pain and discomfort as the treatment progresses, as the sensations either disappear or are no longer the focus of attention.16,31,35,39 However, as the largest changes in OHRQoL occur in the first month of treatment22,23,42,44 longitudinal studies should investigate the impact of orthodontic appliances up until months or years after treatment has ended. Given that self-consciousness and embarrassment were still reported six months after orthodontic appliance insertion, it is suggested that this could indicate long-term psycho-social effects of orthodontic treatment.24
Some factors that have a negative impact on OHRQoL and especially on mental health might impact the emotional and social well-being of children.22,23,26,29 They reported embarrassment, self-consciousness and a lack of confidence due to their appliances.24 Self-confidence can be affected by the visibility of appliances, especially in social situations where attention is focused on the face and mouth.44 This might be as a result of them considering themselves less attractive.46
In contrast, another study was able to show that the appearance of fixed appliances was not a concern.39
It is conceivable that there may have been a change in perception of the appearance over time. Longstaff et al39 discovered that fixed appliances were described as a categorical measure of growing up.
However, the extent to which orthodontic appliance treatment and its impact on social and emotional well-being limits or affects children’s lives, mental health, families, and behavior has not been extensively investigated. Particularly the impact on personality and personal development has not been investigated. Furthermore, it has not been investigated whether functional and socio-emotional limitations have long-term consequences or represent traumatic experiences for children. Especially when it is taken into account that orthodontic appliances are foreign objects inserted into a sensitive area of the body. Additionally, treatment lasts for several years and usually takes place during puberty,49 a time of great physiological and psychosocial change and a period of profound socio-emotional development.20,32,49 Also considering that the perception of facial aesthetics influences psychological development from early childhood to adulthood.50
Only one study explored the impact of orthodontic appliance treatment on the family.21 Orthodontic appliance treatment improved the families’ quality of life, mostly within parental activities and parental emotions. Another study showed similar results and demonstrated that a reduction of an increased overjet by orthodontic treatment caused changes in the family overall, mainly by reducing the emotional pressures faced by parents.51 In comparison, one publication suggested a negative impact of orthodontic appliance treatment on family’s routines.52 Given that only one study investigated the impact of orthodontic appliance treatment on the family, it can be assumed that additional data would be required before comprehensive statements could be made.
Interestingly, the impact of treatment costs on families was not addressed in any study, although the costs of dental treatment are considerably high53 and treatment is associated with financial pressure.5 Lower uptake of orthodontic treatment among patients with lower socio-economic status could be due to financial constraints.54 Children who did not have supplemental insurance were less likely to receive orthodontic treatment.49 It was also shown that children with low annual family income were less likely to receive orthodontic treatment. There is evidence that children and adolescents who are socially disadvantaged have a higher rate of untreated malocclusion, resulting in a significant burden on oral health.55 However, studies have shown that lower socioeconomic group is associated with orthodontic treatment needs.56 Utilization of orthodontic treatment appeared therefore to be largely inequitable Especially when it is taken into account that full reimbursement by health insurance companies may also be a disadvantage, and that overuse of specific groups has been discussed for some time in Germany.1 It is therefore important to investigate the overuse and underuse of certain groups in further studies.
Limitations of the Included Studies
Only one study used a randomized controlled study design.57 Mostly randomization was not used, because it is considered unethical to withhold orthodontic treatment from children who need or desire it.19,22,31,36
The study results reinforce this by showing that children in the waiting/control groups often drop out and/or switch to the treatment group. In addition, the quality of life for children in the waiting group is usually lower than that of children who have already undergone treatment.6,25
The results regarding psychological factors and factors influencing OHRQoL are limited to the subscales and items of the assessments. Additional factors can therefore not be collected and important aspects may be missing. Various assessments were used to measure the achievement of the study objectives, with the CPQ 11–14 and the Oral Health Impact Profile (OHIP-14) being the most widely used. However, using different assessments and self-generated assessments makes it difficult to compare study results.
Further studies with larger sample sizes, a randomized design and longer follow-up periods are required to validate these findings and increase understanding of how orthodontic appliances influences patients OHRQoL, mental health and family. Future studies should also employ other methodological approaches, such as qualitative research to ensure more in-depth and broader insights into the topic. Research topics in the field of clinical decision-making and patient care cannot be adequately understood through quantitative research alone.58
Implication for Practice
Due to the temporary increased risk of negative effects on OHRQoL during treatment, it is important to closely monitor self-perception, mental health, behavior and changes in social behavior during treatment.24 By recognizing that children can experience psychosocial changes when wearing fixed orthodontic appliances, orthodontists can develop appropriate strategies to improve collaboration with patients and ensure successful treatment. Both patients and their families should be informed about the possible side-effects, including the most common impacts on daily life6,23,30 to provide them with more realistic expectations about the treatment outcomes and possible experiences during treatment.31,38
Implications for Future Research
Future studies should investigate the extent to which orthodontic appliance treatment and its impact on social and emotional well-being limits or affects children’s lives, mental health, families, and behavior. This can be done using specific questionnaires and even more detailed qualitative studies. Future studies could also examine the perspectives of patients with different cultural backgrounds, as it is already known that the perception of quality of life depends on the culture of the individual, and therefore the effects of wearing an orthodontic appliance can certainly differ from country to country.23 In addition, a different degree of malocclusion and type of appliance (eg, fixed and removable appliances or clear aligners compared to conventional fixed metal orthodontic appliances) and their influence on children’s mental health, social context and families should be considered and compared in further studies.
Limitations
Because the quality, generalization and study characteristics such as the study population and design were heterogeneous, the comparability of this study’s results are limited and therefore a narrative synthesis was given rather than a meta-analysis.
Conclusions
To our knowledge, this study is the first to summarize the effects of fixed orthodontic appliances treatment on the mental health of children, their social context and their families. However, the extent to which orthodontic appliance treatment and its impact on social and emotional well-being limits or affects children’s lives, mental health, families, and behavior has not been extensively investigated. Results from trials with larger sample sizes, randomized designs, and longer follow-up periods, as well as qualitative research with comprehensive and in-depth data collection and analysis, would provide sufficient information on the influence of orthodontic appliances treatment to help provide patients with comprehensive information. Evidence of the impact of orthodontic appliance treatment on mental health and social context is crucial for deriving evidence-based recommendations. Therefore, the impact of fixed orthodontic appliances should be addressed in further empirical studies.
Acknowledgments
The authors would like to thank native speaker, Michael Bauer, for his language advice.
Funding Statement
The authors declare that no funds, grants, or other support were received during the preparation of this manuscript.
Data Sharing Statement
All data generated or analysed during this study are included in this published article and its supplementary information files.
Author Contributions
All authors made a significant contribution to the work reported, whether that is in the conception, study design, execution, acquisition of data, analysis and interpretation, or in all these areas; took part in drafting, revising or critically reviewing the article; gave final approval of the version to be published; have agreed on the journal to which the article has been submitted; and agree to be accountable for all aspects of the work.
Disclosure
The authors have no relevant financial or non-financial interests to disclose for this work.
References
- 1.Jordan AR, Kuhr K, Ohm C, Frenzel Baudisch N, Kirschneck C. Sechste Deutsche Mundgesundheitsstudie (dms · 6). Zahn- und Kieferfehlstellungen bei Kindern [homepage in the Internet]. 2021. Available from: https://www.idz.institute/publikationen/buecher/sechste-deutsche-mundgesundheitsstudiedms-6/. Accessed November 11, 2024.
- 2.O’Brien K, Kay L, Fox D, Mandall N. Assessing oral health outcomes for orthodontics--measuring health status and quality of life. Community Dental Health. 1998;15(1):22–26. [PubMed] [Google Scholar]
- 3.Tsakos G. Children’s Dental Health Survey 2013 [homepage on the Internet]; 2013. Available from: https://digital.nhs.uk/data-and-information/publications/statistical/children-s-dental-health-survey/child-dental-health-survey-2013-england-wales-and-northern-ireland. Accessed October 2, 2024.
- 4.Seeling S, Prütz F, Butschalowsky H. Uptake of orthodontic treatment by children and adolescents in Germany. Results of the cross-sectional KiGGS Wave 2 study and trends. J Health Monit. 2018;3(4):78–85. doi: 10.17886/RKI-GBE-2018-032 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 5.Hkk. Kieferorthopädische Behandlung von Kindern und Jugendlichen Ergebnisse einer Befragung von behandelten Kindern und Jugendlichen sowie ihren Eltern [Orthodontic treatment by children and adolescents. Results from a survey with treated children and adolescents and their parents] [homepage on the Internet]; 2011. Available from: https://www.hkk.de/fileadmin/dateien/allgemeines_uebergeordnet/reports/gesundheitsreports/hkk_broschuere_kieferorthopaedische_behandlung_a4_web__1_.pdf. Accessed September 20, 2024.
- 6.Oliveira CM De D, Sheiham A. Orthodontic treatment and its impact on oral health-related quality of life in Brazilian adolescents. Journal of Orthodontics. 2004;31(1):20–27. doi: 10.1179/146531204225011364 [DOI] [PubMed] [Google Scholar]
- 7.Zhou Y, Wang Y, Wang X, Volière G, Hu R. The impact of orthodontic treatment on the quality of life a systematic review. BMC Oral Health. 2004;14:1–7. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 8.Zheng DH, Wang XX, Su YR, et al. Assessing changes in quality of life using the Oral Health Impact Profile (OHIP) in patients with different classifications of malocclusion during comprehensive orthodontic treatment. BMC Oral Health. 2015;15:148. doi: 10.1186/s12903-015-0130-7 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 9.Cunningham SJ, Hunt NP. Quality of life and its importance in orthodontics. Journal of Orthodontics. 2001;28(2):152–158. doi: 10.1093/ortho/28.2.152 [DOI] [PubMed] [Google Scholar]
- 10.Mansor N, Saub R, Othman SA. Changes in the oral health-related quality of life 24 h following insertion of fixed orthodontic appliances. J Orthod Sci. 2012;1(4):98–102.3. doi: 10.4103/2278-0203.105880 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 11.Jawaid M, Qadeer TA. Assessment of the changes in the oral health related quality of life 24 hours following insertion of fixed orthodontic appliance components - an observational cross-sectional study conducted at Bahria University medical and dental college Karachi. J Pak Med Assoc. 2019;69(5):677–683. [PubMed] [Google Scholar]
- 12.Taylor KR, Kiyak A, Huang GJ, Greenlee GM, Jolley CJ, King GJ. Effects of malocclusion and its treatment on the quality of life of adolescents. Am J Orthod Dentofacial Orthop. 2009;136:382–392. doi: 10.1016/j.ajodo.2008.04.022 [DOI] [PubMed] [Google Scholar]
- 13.Burnett S, Thompson S, Bird G, Blakemore SJ. Pubertal development of the understanding of social emotions: implications for education. Learn Individ Differ. 2011;21(6):681–689. doi: 10.1016/j.lindif.2010.05.007 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 14.Holder MK, Blaustein JD. Puberty and adolescence as a time of vulnerability to stressors that alter neurobehavioral processes. Front Neuroendocrinol. 2014;35(1):89–110. doi: 10.1016/j.yfrne.2013.10.004 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 15.Stewart FN, Kerr WJ, Taylor PJ. Appliance wear: the patient’s point of view. Eur J Orthod. 1997;19(4):377–382. doi: 10.1093/ejo/19.4.377 [DOI] [PubMed] [Google Scholar]
- 16.Marques LS, Paiva SM, Vieira-Andrade RG, Pereira LJ, Ramos-Jorge ML. Discomfort associated with fixed orthodontic appliances: determinant factors and influence on quality of life. Dental Press J Orthod. 2014;19(3):102–107. doi: 10.1590/2176-9451.19.3.102-107.oar [DOI] [PMC free article] [PubMed] [Google Scholar]
- 17.Tricco AC, Lillie E, Zarin W, et al. Prisma extension for scoping reviews (PRISMA-ScR): checklist and explanation. Ann Intern Med. 2018;169(7):467–473. doi: 10.7326/M18-0850 [DOI] [PubMed] [Google Scholar]
- 18.Peters MDJ, Godfrey C, McInerney P, Munn Z, Tricco AC, Khalil H. Chapter 11: scoping Reviews (2020 version). JBI Manual Evid Synth. 2022;10:10–46658. [Google Scholar]
- 19.Jaeken K, de Llano-Pérula Cadenas M, Lemiere J, Verdonck A, Fieuws S, Willems G. Reported changes in oral health-related quality of life in children and adolescents before, during, and after orthodontic treatment: a longitudinal study. Eur J Orthod. 2019;41(2):125–132. doi: 10.1093/ejo/cjy035 [DOI] [PubMed] [Google Scholar]
- 20.Seehra J, Newton JT, Dibiase AT. Interceptive orthodontic treatment in bullied adolescents and its impact on self-esteem and oral-health-related quality of life. Eur J Orthod. 2013;35(5):615–621. doi: 10.1093/ejo/cjs051 [DOI] [PubMed] [Google Scholar]
- 21.Abreu LG, Corradi-Dias L, Dos Santos TR, Melgaço CA, Lages EMB, Paiva SM. Quality of life of families of adolescents undergoing fixed orthodontic appliance therapy: evaluation of a cohort of parents/guardians of treated and untreated individuals. Int J Paediatr Dent. 2020;30(5):634–641. doi: 10.1111/ipd.12630 [DOI] [PubMed] [Google Scholar]
- 22.Zhang M, McGrath C, Hägg U. Changes in oral health-related quality of life during fixed orthodontic appliance therapy. Am J Orthod Dentofacial Orthop. 2008;133(1):25–29. doi: 10.1016/j.ajodo.2007.01.024 [DOI] [PubMed] [Google Scholar]
- 23.Costa AA, Serra-Negra JM, Bendo CB, Pordeus IA, Paiva SM. Impact of wearing fixed orthodontic appliances on quality of life among adolescents: case-control study. Angle Orthod. 2016;86(1):121–126. doi: 10.2319/100514716.1 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 24.Chen M, Wang DW, Wu LP. Fixed orthodontic appliance therapy and its impact on oral health-related quality of life in Chinese patients. Angle Orthod. 2010;80(1):49–53. doi: 10.2319/010509-9.1 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 25.Feu D, Miguel JA, Celeste RK, Oliveira BH. Effect of orthodontic treatment on oral health-related quality of life. Angle Orthod. 2013;83(5):892–898. doi: 10.2319/100412-781.1 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 26.Agou S, Locker D, Muirhead V, Tompson B, Streiner DL. Does psychological well-being influence oral-health-related quality of life reports in children receiving orthodontic treatment? Am J Orthod Dentofacial Orthop. 2011;139(3):369–377. doi: 10.1016/j.ajodo.2009.05.034 [DOI] [PubMed] [Google Scholar]
- 27.Farzanegan F, Heravi F, Ramezani M. Evaluation of health related quality of life changes after initial orthodontic treatment. Oral Health Prev Dent. 2015;13(2):143–147. doi: 10.3290/j.ohpd.a33087 [DOI] [PubMed] [Google Scholar]
- 28.Feu D, de Oliveira BH, de Oliveira Almeida MA, Kiyak HA, Miguel JAM. Oral health-related quality of life and orthodontic treatment seeking. Am J Orthod Dentofacial Orthop. 2010;138(2):152–159. doi: 10.1016/j.ajodo.2008.09.033 [DOI] [PubMed] [Google Scholar]
- 29.Costa AA, Ferreira MC, Serra-Negra JM, Pordeus IA, Paiva SM. Impact of wearing fixed orthodontic appliances on oral health-related quality of life among Brazilian children. J Orthod. 2011;38(4):275–281. doi: 10.1179/14653121141632 [DOI] [PubMed] [Google Scholar]
- 30.Abreu LG, Dos Santos TR, Melgaço CA, Abreu MHN, Lages EMB, Paiva SM. Impact of orthodontic treatment on adolescents’ quality of life: a longitudinal evaluation of treated and untreated individuals. Qual Life Res. 2018;27(8):2019–2026. doi: 10.1007/s11136-018-1830-7 [DOI] [PubMed] [Google Scholar]
- 31.Johal A, Fleming PS, Al Jawad FA. A prospective longitudinal controlled assessment of pain experience and oral health-related quality of life in adolescents undergoing fixed appliance treatment. Orthod Craniofac Res. 2014;17(3):178–186. doi: 10.1111/ocr.12044 [DOI] [PubMed] [Google Scholar]
- 32.Mandava P, Singaraju GS, Obili S, Nettam V, Vatturu S, Erugu S. Impact of oral health related quality of life and possible role of self-esteem in orthodontic patients: a prospective clinical study. Int J Dent Oral Sci. 2021;94(2):158–169. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 33.Deng X, Wang YJ, Deng F, Liu PL, Wu Y. Psychological well-being, dental esthetics, and psychosocial impacts in adolescent orthodontic patients: a prospective longitudinal study. Am J Orthod Dentofacial Orthop. 2018;153(1):87–96.e2. doi: 10.1016/j.ajodo.2017.05.028 [DOI] [PubMed] [Google Scholar]
- 34.Mattos YP, Guimarães Abreu L, Martins Paiva S. Oral health and well-being of adolescents undergoing orthodontic treatment: perspective of the adolescents and their parents/caregivers. Revista Estomatología. 2019;27(1):4–17. doi: 10.25100/re.v27i1.7680 [DOI] [Google Scholar]
- 35.Fahd CG, Castro GG, Costa ACS, et al. Oral health-related quality of life among adolescents in the first 6 months of fixed orthodontic therapy. Int J Environ Res Public Health. 2023;20(23):7110. doi: 10.3390/ijerph20237110 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 36.Abreu LG, Melgaço CA, Abreu MH, Lages EM, Paiva SM. Impact of the first eight months of orthodontic treatment with a fixed appliance on the families of adolescent patients. Angle Orthod. 2014;84(6):1074–1078. doi: 10.2319/011014-37.1 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 37.Abreu LG, Lages EM, Abreu MH, Pereira LJ, Paiva SM. Preadolescent’s oral health-related quality of life during the first month of fixed orthodontic appliance therapy. J Orthod. 2013;40(3):218–224. doi: 10.1179/1465313313Y.0000000053 [DOI] [PubMed] [Google Scholar]
- 38.Batool M, Huma Amjad S, Farooq M, Jamal F. Effects of orthodontic pain on quality of life of patients undergoing orthodontic treatment in Pakistan. Indo Am J Pharm Sci 2018;5:2462–6. [Google Scholar]
- 39.Longstaff S, Davies K, Benson P. Exploring 10-15-year-old patients’ perspectives of fixed orthodontic treatment. J Orthod. 2021;48(2):110–117. doi: 10.1177/1465312520981077 [DOI] [PubMed] [Google Scholar]
- 40.AlQuraini N, Shah R, Cunningham SJ. Perceptions of outcomes of orthodontic treatment in adolescent patients: a qualitative study. Eur J Orthod. 2019;41(3):294–300. doi: 10.1093/ejo/cjy071 [DOI] [PubMed] [Google Scholar]
- 41.Barbosa de Almeida A, Leite ICG, Alves da Silva G. Brazilian adolescents’ perception of the orthodontic appliance: a qualitative study. Am J Orthod Dentofacial Orthop. 2019;155(4):490–497. doi: 10.1016/j.ajodo.2018.05.020 [DOI] [PubMed] [Google Scholar]
- 42.Banerjee S, Banerjee R, Shenoy U, Agarkar S, Bhattacharya S. Effect of orthodontic pain on quality of life of patients undergoing orthodontic treatment. Indian J Dent Res. 2018;29(1):4–9. doi: 10.4103/ijdr.IJDR_113_16 [DOI] [PubMed] [Google Scholar]
- 43.Bernabé E, Sheiham A, de Oliveira CM. Impacts on daily performances related to wearing orthodontic appliances. Angle Orthod. 2008;78(3):482–486. doi: 10.2319/050207-212.1 [DOI] [PubMed] [Google Scholar]
- 44.Sergl HG, Klages U, Zentner A. Functional and social discomfort during orthodontic treatment--effects on compliance and prediction of patients’ adaptation by personality variables. Eur J Orthod. 2000;22(3):307–315. doi: 10.1093/ejo/22.3.307 [DOI] [PubMed] [Google Scholar]
- 45.Corradi-Dias L, Paiva SM, Pretti H, Pordeus IA, Abreu LG. Impact of the onset of fixed appliance therapy on adolescents’ quality of life using a specific condition questionnaire: a cross-sectional comparison between male and female individuals. J Orthod. 2019;46(3):195–204. doi: 10.1177/1465312519851220 [DOI] [PubMed] [Google Scholar]
- 46.Fonseca LM, Araújo TM, Santos AR, Faber J. Impact of metal and ceramic fixed orthodontic appliances on judgments of beauty and other face-related attributes. Am J Orthod Dentofacial Orthop. 2014;145(2):203–206. doi: 10.1016/j.ajodo.2013.10.016 [DOI] [PubMed] [Google Scholar]
- 47.Patel A, Rodd HD, Baker SR, Marshman Z, Robinson PG, Benson PE. Are social judgements made by children in relation to orthodontic appliances? J Orthod. 2010;37(2):93–99. doi: 10.1179/14653121042948 [DOI] [PubMed] [Google Scholar]
- 48.Oliver RG, Knapman YM. Attitudes to orthodontic treatment. Br J Orthod. 1985;12(4):179–188. doi: 10.1179/bjo.12.4.179 [DOI] [PubMed] [Google Scholar]
- 49.Germa A, Kaminski M, Nabet C. Impact of social and economic characteristics on orthodontic treatment among children and teenagers in France. Oral Epidemiol. 2010;38(2):171–179. doi: 10.1111/j.1600-0528.2009.00515.x [DOI] [PMC free article] [PubMed] [Google Scholar]
- 50.Ukra A, Bennani F, Farella M. Psychological aspects of orthodontics in clinical practice. Part two: general psychosocial wellbeing. Prog Orthod. 2012;13(1):69–77. doi: 10.1016/j.pio.2011.08.001 [DOI] [PubMed] [Google Scholar]
- 51.Pipovic J, Uhac M, Perkovic V, Zigante M, Stefanovic N, Spalj S. Impacts of childhood malocclusion on the family. Auswirkungen kindlicher malokklusion auf die familie. J Orofac Orthop. 2024;85(3):213–222. doi: 10.1007/s00056-022-00422-6 [DOI] [PubMed] [Google Scholar]
- 52.Abreu LG, Melgaço CA, Abreu MH, Lages EM, Paiva SM. Effect of malocclusion among adolescents on family quality of life. Eur Arch Paediatr Dent. 2015;16(4):357–363. doi: 10.1007/s40368-014-0172-6 [DOI] [PubMed] [Google Scholar]
- 53.Ghonmode S, Shrivastava S, Kadaskar AR, Bapat S. Socioeconomic burden of orthodontic treatment: a systematic review. Med Pharm Rep. 2023;96(2):154–163. doi: 10.15386/mpr-2457 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 54.Foster Page LA, Thomson WM. Malocclusion and uptake of orthodontic treatment in Taranaki 12-13-year-olds. N Z Dent J. 2005;101(4):98–111. [PubMed] [Google Scholar]
- 55.Bresnahan BW, Kiyak HA, Masters SH, McGorray SP, Lincoln A, King G. Quality of life and economic burdens of malocclusion in U.S. patients enrolled in Medicaid. J Am Dent Assoc. 2010;141(10):1202–1212. doi: 10.14219/jada.archive.2010.0047 [DOI] [PubMed] [Google Scholar]
- 56.Tickle M, Kay EJ, Bearn D. Socio-economic status and orthodontic treatment need. Oral Epidemiol. 1999;27(6):413–418. doi: 10.1111/j.1600-0528.1999.tb02040.x [DOI] [PubMed] [Google Scholar]
- 57.Albino JE, Lawrence SD, Tedesco LA. Psychological and social effects of orthodontic treatment. J Behav Med. 1994;17(1):81–98. doi: 10.1007/BF01856884 [DOI] [PubMed] [Google Scholar]
- 58.Greenhalgh T, Annandale E, Ashcroft R, et al. An open letter to the BMJ editors on qualitative research [published correction appears in BMJ. BMJ. 2016;352:i563. doi: 10.1136/bmj.i563 [DOI] [PubMed] [Google Scholar]
Associated Data
This section collects any data citations, data availability statements, or supplementary materials included in this article.
Data Availability Statement
All data generated or analysed during this study are included in this published article and its supplementary information files.

