Fig. 2. Daily glucose profile and serum fatty acid profile.
A Twenty-four-hour temporal profile of glucose levels measured by continuous glucose monitoring after a 12-week intervention. The solid lines represent the median glucose, the shaded area is the 25%-75% interval, and the lightly shaded area is the 5%-95% interval. B Calculated 24 h glucose metrics of each group at the end of the trial. Data are shown as box-and whisker plots, centre line, box boundaries, lower and upper whisker represent the median, quartile, minimum and maximum range respectively. P values using two-way ANOVA was displayed. HP-L: n = 14, HP-D: n = 13, HM-L: n = 14 for AUC_sleep, n = 15 for the other parameters, HM-D: n = 13 for AUC_sleep, n = 14 for the other parameters. C Serum free fatty acid (FFA) profile and proportion of different type of FFAs at baseline and after a 12-week intervention. Mixed models (two-sided) with post hoc Bonferroni correction was used. *Ptiming < 0.05. HP-L: high polyunsaturated fat diet at lunch; HP-D: high polyunsaturated fat diet at dinner; HM-L: high monounsaturated fat diet at lunch; HM-D: high monounsaturated fat diet at dinner; SD: standard deviation; eHbA1C: estimated glycated hemoglobin A1c; MAGE: mean amplitude of glycemic excursion; AUC: area under the curve; SFA: saturated fatty acid; MUFA: monounsaturated fatty acid; PUFA: polyunsaturated fatty acid.