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. 2025 May 7;25:670. doi: 10.1186/s12879-025-10980-w

Table 2.

Correlation of minimal inhibitory concentrations (MIC) values of Benzalkonium chloride and chlorhexidine with resistance profiles (MDR, XDR, PDR) in Klebsiella pneumoniae isolates (N = 50)

Resistance patterns Benzalkonium chloride MIC (µg/mL) chlorhexidine MIC (µg/mL) p-values
Mean Median Range Mean Median Range
MDR(Multidrug resistance) 23.00 16.00 8–64 59.67 64.00 8-128 *P-value = 0.005
XDR(Extensively drug resistance) 43.60 16.00 8-256 63.00 64.00 4-128 **P-value = 0.670
PDR(Pan-drug resistance) 85.33 64.00 32–256 48.00 40.00 8-128

P1 = 0.459

P2 = 0.001

P3 = 0.006

*p-value: Represents the statistical analysis of benzalkonium chloride MIC values in relation to resistance patterns

**P-value: Represents the statistical analysis of chlorhexidine MIC values in relation to resistance patterns

P1: Compares benzalkonium chloride MIC values between MDR and XDR strains

P2: Compares benzalkonium chloride MIC values between MDR and PDR strains

P3: Compares benzalkonium chloride MIC values between XDR and PDR strains