Fig. 2.

Effect of taurine on the cellular senescence induced by chronic CCl4 injection. (A) p21 expression was measured in the liver by qPCR. The expression level was normalized by the expression level of 28S ribosomal RNA. Values are shown fold of Control. n = 6–8. ∗p < 0.05 (post-hoc Bonferroni test). (B) Frozen section of livers was immunostained with anti-p21and anti-p16 antibodies. Arrowheads indicate positive cells. Positive cells per microscopic images were calculated from 5 images per samples for 4 samples for each group. ∗p < 0.05 (Student's t-test).