Table 2.

Multitrait meta-analysis between depression and risk factors in East Asians

Risk Factors	SNP	CHR	BP	A1	A2	Trait1		Trait2		MTAG		Genes	Annotation
						Beta	P Value	Beta	P Value	Beta	P Value
BMI	rs13029479	2	655222	A	G	0.101	0.007	−0.052	5.40E-17	0.035	1.31E-09	TMEM18	New
	rs4802269	19	46167469	G	A	−0.07	4.94E-04	0.042	4.60E-16	−0.021	5.01E-11	GIPR	New
Weight	rs4802269	19	46167469	G	A	−0.07	4.94E-04	0.037	4.30E-17	−0.021	1.25E-08	GIPR	New
HDL	rs11066015	12	112168009	A	G	−0.073	0.001	−0.122	1.60E-109	−0.033	8.23E-21	ALDH2	New
	rs35626903	16	56431613	G	A	−0.071	6.24E-06	−0.028	2.50E-09	−0.018	2.52E-09	AMFR	New
TBL	rs12993249	2	234479377	A	G	−0.055	1.40E-03	−0.123	1.60E-208	−0.044	2.55E-46	USP40	New
	rs10770745	12	20986617	T	G	−0.067	8.73E-04	−0.031	2.60E-13	−0.018	9.50E-09	SLCO1B3-SLCO1B7	New
	rs11066015	12	112168009	A	G	−0.073	1.47E-03	−0.035	1.30E-15	−0.02	4.66E-09	ALDH2	New
Type 2 diabetes	rs10013800	4	71731236	T	C	−0.092	4.21E-05	0.081	2.21E-10	−0.023	1.19E-11	GRSF1	New
	rs10974438	9	4291928	A	C	0.045	0.005	0.078	2.35E-16	0.017	4.95E-12	GLIS3	New
	rs11074451	16	20336257	A	G	0.1	2.27E-04	0.103	9.12E-11	0.026	5.61E-11	GP2	New
Drugs used in diabetes use measurement	rs6850072	4	71725868	A	G	0.074	2.37E-04	−0.086	1.14E-12	0.022	1.25E-11	GRSF1	New
	rs10974438	9	4291928	A	C	0.045	0.005	0.072	1.91E-12	0.016	1.64E-09	GLIS3	New
	rs11074451	16	20336257	A	G	0.1	2.27E-04	0.114	2.00E-11	0.028	5.46E-11	GP2	New
	rs662872	18	8881068	T	C	−0.084	1.80E-06	0.038	7.27E-04	−0.016	2.02E-08	MTCL1	New

Note: The sections labeled “Trait 1” and “Trait 2” display the statistical results from the original GWAS for the traits involved in the MTAG analysis, MTAG section of the table presents the MTAG results specific to Trait 1. Trait1, depression; Trait2, risk factors.