TABLE 4.

Univariable and multivariable analyses of the polymorphic loci with migraine susceptibility.

SNPs	Dominant model	Univariable OR	P	Multivariable OR	P
TNF-α-308 G/A (rs1800629)	GA + AA/GG	1.011 (0.594–1.721)	0.967	0.978 (0.573–1.671)	0.935
TNF-α-857 C/T (rs1799724)	CT + TT/CC	1.218 (0.776–1.913)	0.391	1.219 (0.771–1.928)	0.396
TNF-α-238G/A (rs361525)	GA + AA/GG	1.010 (0.469–2.175)	0.979	1.018 (0.472–2.195)	0.963
IL1B-3953 C/T (rs1143634)	CT + TT/CC	2.244 (1.030–4.890)	0.042*	2.315 (1.053–5.090)	0.037*
IL1RN −2018 T/C (rs419598)	CT + CC/TT	1.072 (0.546–2.106)	0.840	1.133 (0.573–2.239)	0.719

OR: odds ratio; CI: confidence interval.

The multivariable analysis was adjusted for migraine type (MA/MO), family history, age, and sex. The * symbol represents P s 0.05, which is statistically significant.